Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 18/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.53 |
| ▸ | NPY4R | P50391 | 2/20 | 0.53 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.46 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901712 | 0.91 | NPY1R (0.57) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL7040755 | 0.90 | NPY1R (0.55) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL7036808 | 0.84 | NPY1R (0.61) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL7038160 | 0.83 | NPY1R (0.61) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL7037374 | 0.83 | NPY1R (0.57) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL6899864 | 0.83 | NPY1R (0.71) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL7059807 | 0.83 | NPY1R (0.71) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL7750618 | 0.83 | NPY1R (0.60) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL8528679 | 0.82 | NPY1R (0.59) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL8119876 | 0.80 | NPY1R (0.57) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-B1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | THOMAE GMBH DR K (DE) | 2003-03-26 | — | — | EP | claimed |
| EP-1337257-A4 | USE OF NEUROPEPTIDE-Y ANTAGONISTS IN TREATMENT OF ALCOHOLISM | UNIV CALIFORNIA (US) | 2004-04-07 | — | — | EP | disclosed |
| EP-1337257-A1 | USE OF NEUROPEPTIDE-Y ANTAGONISTS IN TREATMENT OF ALCOHOLISM | The Regents of the University of California (US) | 2003-08-27 | — | — | EP | disclosed |
| EP-0885186-B1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | THOMAE GMBH DR K (DE) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002028393-A1 | USE OF NEUROPEPTIDE-Y ANTAGONISTS IN TREATMENT OF ALCOHOLISM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-04-11 | — | — | WO | disclosed |