Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 16/20 | 0.57 |
| ▸ | NPY4R | P50391 | 4/20 | 0.57 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.57 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.49 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901901 | 0.91 | NPY1R (0.53) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL7040755 | 0.88 | NPY1R (0.55) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL7059807 | 0.86 | NPY1R (0.71) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL6899864 | 0.86 | NPY1R (0.71) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL7036808 | 0.86 | NPY1R (0.61) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL7037374 | 0.85 | NPY1R (0.57) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL7038160 | 0.85 | NPY1R (0.61) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL7750618 | 0.84 | NPY1R (0.60) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| Trifluoroacetic Acid SCHEMBL649618 | 0.81 | NPY1R (0.66) | NPY1RNPY4RNPY5RMCHR1 | |
| SCHEMBL7751683 | 0.81 | NPY1R (0.62) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-B1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | THOMAE GMBH DR K (DE) | 2003-03-26 | — | — | EP | claimed |
| US-20040029953-A1 | Use of neuropeptide-y antagonists in treatment of alcoholism | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-02-12 | — | — | US | disclosed |
| EP-0885186-B1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | THOMAE GMBH DR K (DE) | 2003-03-26 | — | — | EP | disclosed |