Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.48 |
| ▸ | NQO2 | P16083 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691814 | 0.89 | ALDH1A1 (0.47) | HSP90AA1HSP90AB1NQO2ALDH1A1KDM4E | |
| SCHEMBL30189894 | 0.88 | NQO2 (0.43) | HSP90AA1HSP90AB1NQO2ALDH1A1KDM4E | |
| SCHEMBL19782783 | 0.88 | NQO2 (0.43) | HSP90AA1HSP90AB1NQO2ALDH1A1KDM4E | |
| SCHEMBL7057168 | 0.83 | HSP90AA1 (0.54) | HSP90AA1HSP90AB1ALDH1A1KDM4EHPGD | |
| SCHEMBL6697802 | 0.80 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1NQO2ALDH1A1KDM4E | |
| SCHEMBL6690657 | 0.80 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1NQO2ALDH1A1KDM4E | |
| SCHEMBL8040045 | 0.78 | NQO2 (0.47) | NQO2ALDH1A1KDM4EHPGDELANE | |
| SCHEMBL84829 | 0.76 | CYP3A4 (0.57) | NQO2ALDH1A1KDM4EHPGDELANE | |
| SCHEMBL2748734 | 0.76 | NQO2 (0.46) | NQO2ALDH1A1KDM4EHPGDELANE | |
| SCHEMBL2749006 | 0.76 | ALDH1A1 (0.58) | NQO2ALDH1A1KDM4EHPGDELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945482-B1 | Rubber composition for tire tread and pneumatic tire using same | BRIDGESTONE CORP (JP) | 2004-01-28 | — | — | EP | disclosed |
| US-6242522-B1 | A DIENE BASED SYNTHETIC RUBBER OR NATURAL RUBBER BLEND CONTAINING BUTADIENE-STYRENE RUBBER, ALUMINUM HYDROXIDE POWDER, SILICA POWDER, CARBON BLACK; LOW FUEL CONSUMPTION AND WEAR RESISTANCE; IMPROVED GRIPPING IN WET AND COLD SITUATIONS | BRIDGESTONE CORPORATION (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0948029-A2 | High pressure discharge lamp | NGK INSULATORS, LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |