SCHEMBL6697802

SCHEMBL6697802

COc1cccc2nc(SNC(C)(C)C)sc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.39
HSP90AB1 P08238 1/20 0.39
NQO2 P16083 5/20 0.37
CASR P41180 1/20 0.36
ALDH1A1 P00352 5/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
MAPT P10636 3/20 0.35
LMNA P02545 2/20 0.35
HTT P42858 1/20 0.35
HIF1A Q16665 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
KDM4E B2RXH2 2/20 0.35
HPGD P15428 1/20 0.35
GAA P10253 1/20 0.35
ELANE P08246 1/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6689394 0.87 HSP90AA1 (0.44) HSP90AA1HSP90AB1ALDH1A1MEN1KMT2A
SCHEMBL6697899 0.83 HSP90AA1 (0.42) HSP90AA1HSP90AB1ALDH1A1NPC1RAB9A
SCHEMBL6690657 0.80 HSP90AA1 (0.43) HSP90AA1HSP90AB1NQO2ALDH1A1MEN1
SCHEMBL6901949 0.80 HSP90AA1 (0.48) HSP90AA1HSP90AB1NQO2ALDH1A1MEN1
SCHEMBL6691814 0.80 ALDH1A1 (0.47) HSP90AA1HSP90AB1NQO2ALDH1A1MEN1
SCHEMBL6689383 0.79 ALDH1A1 (0.52) ALDH1A1MEN1KMT2AMAPTLMNA
SCHEMBL30189894 0.79 NQO2 (0.43) HSP90AA1HSP90AB1NQO2ALDH1A1MEN1
SCHEMBL19782783 0.79 NQO2 (0.43) HSP90AA1HSP90AB1NQO2ALDH1A1MEN1
SCHEMBL6690584 0.75 HPGD (0.61) HSP90AA1ALDH1A1MEN1KMT2ALMNA
SCHEMBL29370541 0.74 ALDH1A1 (0.58) ALDH1A1MAPTLMNAHTTHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0869016-B1 Pneumatic radial tires BRIDGESTONE CORP (JP) 2004-03-03 EP disclosed
EP-0945482-B1 Rubber composition for tire tread and pneumatic tire using same BRIDGESTONE CORP (JP) 2004-01-28 EP disclosed
EP-0890605-B1 Pneumatic tire BRIDGESTONE CORP (JP) 2003-04-23 EP disclosed
EP-1277795-A2 Pneumatic tire BRIDGESTONE CORPORATION (JP) 2003-01-22 EP disclosed
US-20020010283-A1 RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2002-01-24 US disclosed
US-6336486-B1 Pneumatic radical tire having cap base tread BRIDGESTONE CORPORATION (JP) 2002-01-08 US disclosed
US-6242522-B1 A DIENE BASED SYNTHETIC RUBBER OR NATURAL RUBBER BLEND CONTAINING BUTADIENE-STYRENE RUBBER, ALUMINUM HYDROXIDE POWDER, SILICA POWDER, CARBON BLACK; LOW FUEL CONSUMPTION AND WEAR RESISTANCE; IMPROVED GRIPPING IN WET AND COLD SITUATIONS BRIDGESTONE CORPORATION (JP) 2001-06-05 US disclosed
US-6186204-B1 EXCELLENT STABILITY AND CONTROLLABILITY ON WET ROADS OR A COMBINATION OF STABILITY AND CONTROLLABILITY ON WET ROADS AND EXCELLENT COMFORT OF RIDE EVEN WHEN A VEHICLE IS VIBRATING THROUGHOUT THE LIFE OF THE PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2001-02-13 US disclosed
EP-0948029-A2 High pressure discharge lamp NGK INSULATORS, LTD. (JP) 1999-10-06 EP disclosed
EP-0890605-A2 Pneumatic tire BRIDGESTONE CORPORATION (JP) 1999-01-13 EP disclosed
EP-0869016-A2 Pneumatic radial tires Bridgestone Corporation (JP) 1998-10-07 EP disclosed
EP-0854168-A1 Rubber composition Bridgestone Corporation (JP) 1998-07-22 EP disclosed