SCHEMBL6902044

SCHEMBL6902044

O=C(Cl)OCC#CCOC(=O)Cl

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
MEN1 O00255 1/20 0.30
THRB P10828 1/20 0.30
RECQL P46063 1/20 0.30
BLM P54132 1/20 0.30
KMT2A Q03164 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11258130 0.89
SCHEMBL18166785 0.87
SCHEMBL11305843 0.84
SCHEMBL649854 0.84
SCHEMBL585989 0.77
SCHEMBL10386492 0.75 ALDH1A1 (0.36) ALDH1A1
SCHEMBL16286097 0.71 KMT2A (0.31) KMT2A
SCHEMBL11813098 0.71 TSHR (0.33) MEN1THRBRECQLBLMKMT2A
SCHEMBL11834057 0.70 MMP1 (0.35)
SCHEMBL10249594 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1208014-B1 POSITIVE ACTING PHOTORESIST COMPOSITION AND IMAGEABLE ELEMENT CREO IL LTD (IL) 2004-04-14 EP disclosed
US-6541181-B1 Heat sensitive element on lithographic substrate CREO IL. LTD. (IL) 2003-04-01 US disclosed
US-6255033-B1 ACETALIZATION OF A PARTIALLY HYDROLYZED POLYVINYL ACETATE WITH A MIXTURE OF AN ACYCLIC ALDEHYDE AND AN AROMATIC ALDEHYDE CREO, LTD. (IL) 2001-07-03 US disclosed