SCHEMBL69021

SCHEMBL69021

CC(c1ccc(O)cc1Cl)c1ccc(O)cc1Cl

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.63
HSD17B10 Q99714 1/20 0.52
TYR P14679 1/20 0.46
TTR P02766 1/20 0.45
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.42
HTT P42858 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
ESR2 Q92731 4/20 0.41
PDCD1 Q15116 1/20 0.41
CD274 Q9NZQ7 1/20 0.41
PDE2A O00408 1/20 0.40
MEN1 O00255 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30234474 1.00 ESR1 (0.63) ESR1HSD17B10TYRTTRLMNA
SCHEMBL3242230 0.88 ESR1 (0.56) ESR1HSD17B10TYRTTRLMNA
SCHEMBL6742674 0.86 ESR1 (0.63) ESR1HSD17B10TYRTTRLMNA
SCHEMBL10750898 0.79 ESR1 (0.66) ESR1HSD17B10TYRTTRLMNA
SCHEMBL22354939 0.79 ESR1 (0.55) ESR1HSD17B10TYRTTRLMNA
SCHEMBL20060877 0.79 ESR1 (0.65) ESR1HSD17B10TTRCA12CA1
SCHEMBL51618 0.76 TYR (0.70) ESR1TYRLMNACA12CA1
SCHEMBL18097894 0.76 TP53 (0.68) HSD17B10LMNATP53HTTPDE2A
SCHEMBL27351915 0.76 ESR1 (0.73) ESR1HSD17B10TTRLMNATP53
SCHEMBL9763719 0.74 ESR2 (0.47) ESR1TYRLMNAESR2PDCD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1349 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1660560-B1 PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETEHRIMIDES SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-03-23 EP claimed
CN-103497334-A Copolyetherimides SABIC INNOVATIVE PLASTICS IP 2014-01-08 CN claimed
EP-2649111-A1 ISOSORBIDE-CONTAINING POLYCARBONATES AND THEIR PREPARATION SABIC Innovative Plastics IP B.V. (NL) 2013-10-16 EP claimed
EP-1581594-B1 POLYCARBONATE MOLDING COMPOSITIONS AND ARTICLES WITH IMPROVED SURFACE AESTHETICS SABIC INNOVATIVE PLASTICS IP (NL) 2013-03-27 EP claimed
US-8372943-B2 Isosorbide—containing polycarbonates and their preparation SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-02-12 US claimed
US-8222347-B2 Polyester-polycarbonate compositions SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-07-17 US claimed
US-20120149863-A1 ISOSORBIDE - CONTAINING POLYCARBONATES AND THEIR PREPARATION SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2012-06-14 US claimed
WO-2012078825-A1 ISOSORBIDE-CONTAINING POLYCARBONATES AND THEIR PREPARATION SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-06-14 WO claimed
JP-4768635-B2 2011-09-07 JP claimed
EP-1546249-B1 FLAME RETARDANT RESINOUS COMPOSITIONS AND METHOD SABIC INNOVATIVE PLASTICS IP (NL) 2011-03-16 EP claimed
WO-2004005368-A1 POLYESTERCARBONATES AND METHODS OF MANUFACTURE GENERAL ELECTRIC COMPANY (US) 2004-01-15 WO claimed
US-20030195325-A1 METHOD FOR COPOLYESTERCARBONATE SYNTHESIS GENERAL ELECTRIC COMPANY 2003-10-16 US claimed
WO-2003082949-A1 METHOD FOR COPOLYESTERCARBONATE SYNTHESIS GENERAL ELECTRIC COMPANY (US) 2003-10-09 WO claimed
US-6613824-B2 Composition comprising aromatic carbonate, polymer derived from vinyl aromatic, unsaturated nitrile or (meth)acrylate ester monomers, rubber modified graft copolymer, organic phosphorus species, antidrip agent, perfluoroalkanesulfonate GENERAL ELECTRIC COMPANY 2003-09-02 US claimed
US-20030139504-A1 Flame retardant resinous compositions and method GENERAL ELECTRIC COMPANY 2003-07-24 US claimed
US-20030109650-A1 Flame retardant resinous compositions and method GENERAL ELECTRIC COMPANY 2003-06-12 US claimed
WO-2003042305-A1 FLAME RETARDANT RESINOUS COMPOSITIONS AND METHOD OF MAKING THE SAME GENERAL ELECTRIC COMPANY (A NEW YORK CORPORATION) (US) 2003-05-22 WO claimed
WO-2003042303-A1 FLAME RETARDANT RESINOUS COMPOSITIONS AND METHOD GENERAL ELECTRIC COMPANY (A NEW YORK CORPORATION) (US) 2003-05-22 WO claimed
US-6552158-B1 Optical disks with polycarbonate protective layer which is a copolymer of a bis(hydroxyaryl)cyclohexane and an aromatic dihydroxy compound; heat resistance; high density optical data storage and recordable media GENERAL ELECTRIC COMPANY 2003-04-22 US claimed
US-4463163-A Polycarbonate from 4,4'-bis (4-hydroxyphenyl thio)biphenyls MOBAY CHEMICAL CORPORATION (US) 1984-07-31 US claimed