SCHEMBL6902265

SCHEMBL6902265

CCOC(=O)CCc1cccc(C(C)C)c1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 3/20 0.56
CYP4A11 Q02928 3/20 0.56
ALDH1A1 P00352 2/20 0.50
GAA P10253 1/20 0.50
NLRP3 Q96P20 3/20 0.49
LMNA P02545 3/20 0.44
FAAH O00519 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
GABRA1 P14867 1/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44
GABRB1 P18505 1/20 0.44
GABRG2 P18507 1/20 0.44
PTGS1 P23219 1/20 0.44
SLC6A2 P23975 1/20 0.44
HTR2C P28335 1/20 0.44
GABRB3 P28472 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6904692 0.92 CYP4F2 (0.53) CYP4F2CYP4A11ALDH1A1GAANLRP3
SCHEMBL5598458 0.89 MAPK1 (0.46) CYP4F2CYP4A11ALDH1A1GAANLRP3
SCHEMBL6902810 0.89 CYP4F2 (0.54) CYP4F2CYP4A11ALDH1A1GAANLRP3
SCHEMBL19289921 0.83 CYP4F2 (0.54) CYP4F2CYP4A11ALDH1A1GAANLRP3
SCHEMBL490584 0.82 IAPP (0.64) CYP4F2CYP4A11ALDH1A1GAANLRP3
SCHEMBL6904647 0.81 CYP4F2 (0.51) CYP4F2CYP4A11ALDH1A1GAANLRP3
SCHEMBL6901879 0.81 SLC6A2 (0.42) CYP4F2CYP4A11NLRP3LMNAFAAH
SCHEMBL11214621 0.79 CYP4F2 (0.59) CYP4F2CYP4A11ALDH1A1GAANLRP3
SCHEMBL5598808 0.79 CDYL (0.42) CYP4F2CYP4A11ALDH1A1GAATSHR
SCHEMBL5120475 0.78 CYP4F2 (0.57) CYP4F2CYP4A11ALDH1A1GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1430017-A2 SUBSTITUTED PHENOL COMPOUNDS USEFUL FOR ANESTHESIA AND SEDATION Theravance, Inc. (US) 2004-06-23 EP disclosed
US-6680322-B2 FOR THERAPY OF ASTHMA, ALLERGIC RHINITIS, RESPIRATORY SYSTEM DISORDERS OSI PHARMACEUTICALS, INC. 2004-01-20 US disclosed
WO-2003026632-A2 SUBSTITUTED PHENOL COMPOUNDS USEFUL FOR ANESTHESIA AND SEDATION THERAVANCE, INC. (US) 2003-04-03 WO disclosed