Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | IAPP | P10997 | 4/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6904647 | 0.92 | CYP4F2 (0.51) | CYP4F2CYP4A11ALDH1A1GAATSHR | |
| SCHEMBL5598808 | 0.90 | CDYL (0.42) | CYP4F2CYP4A11ALDH1A1GAATSHR | |
| SCHEMBL6902265 | 0.89 | CYP4F2 (0.56) | CYP4F2CYP4A11ALDH1A1GAATSHR | |
| SCHEMBL6904692 | 0.81 | CYP4F2 (0.53) | CYP4F2CYP4A11ALDH1A1GAATSHR | |
| SCHEMBL490584 | 0.80 | IAPP (0.64) | CYP4F2CYP4A11ALDH1A1GAAIAPP | |
| SCHEMBL5598458 | 0.78 | MAPK1 (0.46) | CYP4F2CYP4A11ALDH1A1GAATSHR | |
| SCHEMBL6870041 | 0.78 | TSHR (0.53) | TSHRIAPPLMNA | |
| SCHEMBL10486191 | 0.77 | GABRA1 (0.59) | TSHRLMNA | |
| SCHEMBL11214621 | 0.77 | CYP4F2 (0.59) | CYP4F2CYP4A11ALDH1A1GAAIAPP | |
| SCHEMBL5120475 | 0.76 | CYP4F2 (0.57) | CYP4F2CYP4A11ALDH1A1GAAIAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430017-A2 | SUBSTITUTED PHENOL COMPOUNDS USEFUL FOR ANESTHESIA AND SEDATION | Theravance, Inc. (US) | 2004-06-23 | — | — | EP | disclosed |
| WO-2003026632-A2 | SUBSTITUTED PHENOL COMPOUNDS USEFUL FOR ANESTHESIA AND SEDATION | THERAVANCE, INC. (US) | 2003-04-03 | — | — | WO | disclosed |