SCHEMBL6904647

SCHEMBL6904647

CCOC(=O)CCCc1cccc(C(C)CC)c1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 3/20 0.51
CYP4A11 Q02928 3/20 0.51
SMN1; SMN2 Q16637 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
ALOX5 P09917 1/20 0.41
ALDH1A1 P00352 1/20 0.41
GAA P10253 1/20 0.41
CYP4Z1 Q86W10 2/20 0.40
CYP4F11 Q9HBI6 1/20 0.40
CYP4F12 Q9HCS2 1/20 0.40
NLRP3 Q96P20 2/20 0.40
TSHR P16473 1/20 0.40
USP2 O75604 1/20 0.39
HSD17B10 Q99714 1/20 0.39
DRD2 P14416 1/20 0.38
TBXAS1 P24557 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6902810 0.92 CYP4F2 (0.54) CYP4F2CYP4A11SMN1; SMN2ALDH1A1GAA
SCHEMBL6904692 0.90 CYP4F2 (0.53) CYP4F2CYP4A11SMN1; SMN2CYP1A2CYP3A4
SCHEMBL5598808 0.82 CDYL (0.42) CYP4F2CYP4A11ALOX5ALDH1A1GAA
SCHEMBL6902265 0.81 CYP4F2 (0.56) CYP4F2CYP4A11SMN1; SMN2CYP1A2CYP3A4
SCHEMBL28072636 0.81 CYP4F2 (0.58) CYP4F2CYP4A11SMN1; SMN2CYP1A2CYP3A4
SCHEMBL20030391 0.80 CYP4F2 (0.61) CYP4F2CYP4A11SMN1; SMN2CYP1A2CYP3A4
SCHEMBL13410217 0.79 TSHR (0.50) CYP1A2CYP3A4ALOX5TSHRIAPP
SCHEMBL17284798 0.79 CYP4F2 (0.56) CYP4F2CYP4A11SMN1; SMN2CYP1A2CYP3A4
SCHEMBL27501902 0.79 CYP4F2 (0.56) CYP4F2CYP4A11SMN1; SMN2CYP1A2CYP3A4
SCHEMBL6870041 0.76 TSHR (0.53) CYP1A2CYP3A4ALOX5TSHRIAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1430017-A2 SUBSTITUTED PHENOL COMPOUNDS USEFUL FOR ANESTHESIA AND SEDATION Theravance, Inc. (US) 2004-06-23 EP disclosed
WO-2003026632-A2 SUBSTITUTED PHENOL COMPOUNDS USEFUL FOR ANESTHESIA AND SEDATION THERAVANCE, INC. (US) 2003-04-03 WO disclosed