Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2783831 | 0.98 | TSHR (0.45) | TSHRSMN1; SMN2 | |
| SCHEMBL18186752 | 0.77 | SMN1; SMN2 (0.44) | TSHRSMN1; SMN2 | |
| SCHEMBL18186751 | 0.77 | SMN1; SMN2 (0.44) | TSHRSMN1; SMN2 | |
| SCHEMBL14915013 | 0.73 | — | — | |
| SCHEMBL28108367 | 0.69 | ADH1B (0.35) | — | |
| SCHEMBL4281878 | 0.68 | TSHR (0.64) | TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL4274173 | 0.66 | TSHR (0.61) | TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL4269639 | 0.66 | TSHR (0.61) | TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL2309309 | 0.66 | — | — | |
| SCHEMBL103963 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204687-B1 | SILANE ENDCAPPED MOISTURE CURABLE COMPOSITIONS | GEN ELECTRIC (US) | 2004-10-20 | — | — | EP | claimed |
| JP-2003508561-A | — | — | 2003-03-04 | — | — | JP | claimed |
| EP-1204687-A1 | SILANE ENDCAPPED MOISTURE CURABLE COMPOSITIONS | Crompton Corporation (US) | 2002-05-15 | — | — | EP | claimed |
| WO-2001016201-A1 | SILANE ENDCAPPED MOISTURE CURABLE COMPOSITIONS | CROMPTON CORPORATION (US) | 2001-03-08 | — | — | WO | claimed |
| US-6197912-B1 | AMINO-FUNCTIONAL SILANES OR SILOXANES; HEAT AND TEAR RESISTANCE, ELONGATION | CK WITCO CORPORATION | 2001-03-06 | — | — | US | claimed |