SCHEMBL7943548

SCHEMBL7943548

CCNCCN(CC)CC[Si](C)(C)CCN(CC)CCNCC

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.32
MEN1 O00255 1/20 0.32
GLA P06280 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP1A2 P05177 1/20 0.31
TSHR P16473 1/20 0.31
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3972281 0.84 CYP2C19 (0.43) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL9079152 0.82 CYP2C19 (0.41) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL4192702 0.80 CYP2C19 (0.39) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL250410 0.79 CYP2C19 (0.43) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL23975243 0.78 TSHR (0.42) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL6902349 0.77 SIGMAR1 (0.30)
Hydrochloric Acid SCHEMBL29183274 0.77 CYP2C19 (0.41) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL8803099 0.77 CYP2C19 (0.41) CYP2C19MEN1GLAKMT2ACYP1A2
Ammonia Solution, Strong SCHEMBL11798888 0.77 CYP2C19 (0.41) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL12069860 0.76 PRMT3 (0.40) CYP2C19MEN1GLAKMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6274561-B1 SYNERGISTIC MIXTURE OF SILAMINE AND ADRIAMYCIN; SIDE EFFECT REDUCTION JAPAN SCIENCE & TECHNOLOGY CORP. (JP) 2001-08-14 US claimed