Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6898634 | 0.91 | KDM4E (0.36) | KDM4ECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7119526 | 0.84 | KDM4E (0.34) | KDM4ECHRM2CHRM4CHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL6898185 | 0.82 | CHRM2 (0.34) | KDM4ECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6902547 | 0.81 | CYP1A1 (0.38) | KDM4ECHRM2CHRM4CHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL6898454 | 0.73 | KDM4E (0.33) | KDM4ECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6897870 | 0.73 | CHRM2 (0.32) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6903109 | 0.72 | HTR6 (0.35) | KDM4ECHRM2CHRM4CHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL6902739 | 0.71 | HTR6 (0.34) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6903206 | 0.68 | KDM4E (0.39) | KDM4ECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6904348 | 0.67 | CCR1 (0.37) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033371-B1 | Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2004-01-28 | — | — | EP | claimed |