Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CCR1 | P32246 | 2/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
| ▸ | CCR8 | P51685 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6904348 | 0.82 | CCR1 (0.37) | KDM4EMAPTLMNACCR1CCR5 | |
| Hydrochloric Acid SCHEMBL6895316 | 0.81 | KDM4E (0.39) | KDM4ESMN1; SMN2TP53NPC1ALDH1A1 | |
| SCHEMBL7119526 | 0.70 | KDM4E (0.34) | KDM4ESMN1; SMN2NPC1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL6901138 | 0.69 | KDM4E (0.43) | KDM4ESMN1; SMN2TP53NPC1ALDH1A1 | |
| SCHEMBL6901048 | 0.69 | KDM4E (0.46) | KDM4ESMN1; SMN2TP53NPC1ALDH1A1 | |
| SCHEMBL6898078 | 0.68 | KDM4E (0.40) | KDM4ESMN1; SMN2TP53NPC1ALDH1A1 | |
| SCHEMBL31607260 | 0.65 | KDM4E (0.63) | KDM4ESMN1; SMN2TP53NPC1ALDH1A1 | |
| SCHEMBL29484714 | 0.65 | KDM4E (0.63) | KDM4ESMN1; SMN2TP53NPC1ALDH1A1 | |
| SCHEMBL57525 | 0.65 | KDM4E (0.63) | KDM4ESMN1; SMN2TP53NPC1ALDH1A1 | |
| SCHEMBL31473547 | 0.65 | KDM4E (0.63) | KDM4ESMN1; SMN2TP53NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033371-B1 | Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2004-01-28 | — | — | EP | claimed |