SCHEMBL6902838

SCHEMBL6902838

CC(C)(c1ccccc1Oc1cccc(N)c1N)c1ccccc1Oc1cccc(N)c1N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
ADRA2B P18089 1/20 0.39
PTGS1 P23219 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
GAA P10253 2/20 0.38
CD44 P16070 1/20 0.36
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
CRHBP P24387 1/20 0.35
CRHR2 Q13324 1/20 0.35
CYP1A2 P05177 2/20 0.33
CYP2C19 P33261 2/20 0.33
CYP2C9 P11712 1/20 0.33
RCE1 Q9Y256 1/20 0.33
CYP3A4 P08684 3/20 0.31
TSHR P16473 1/20 0.31
PIK3CA P42336 1/20 0.31
ALOX15 P16050 1/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1966245 0.87 ALDH1A1 (0.48) ALDH1A1ADRA2BPTGS1TDP1GAA
SCHEMBL30530134 0.87 ALDH1A1 (0.48) ALDH1A1ADRA2BPTGS1TDP1GAA
SCHEMBL3743371 0.85 ALDH1A1 (0.47) ALDH1A1ADRA2BPTGS1TDP1GAA
SCHEMBL21796060 0.80 ALDH1A1 (0.46) ALDH1A1ADRA2BPTGS1TDP1GAA
SCHEMBL28416885 0.80 ALDH1A1 (0.46) ALDH1A1ADRA2BPTGS1TDP1GAA
SCHEMBL711288 0.80 CD44 (0.46) ALDH1A1ADRA2BPTGS1TDP1GAA
SCHEMBL1501337 0.77 ALDH1A1 (0.42) ALDH1A1ADRA2BPTGS1TDP1GAA
SCHEMBL8512559 0.76 CD44 (0.48) ALDH1A1ADRA2BPTGS1TDP1GAA
SCHEMBL397028 0.76 ALDH1A1 (0.48) ALDH1A1ADRA2BPTGS1TDP1GAA
SCHEMBL10392465 0.76 ALDH1A1 (0.54) ALDH1A1ADRA2BPTGS1TDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1114845-B1 PASTE COMPOSITION, AND PROTECTIVE FILM AND SEMICONDUCTOR DEVICE BOTH OBTAINED WITH THE SAME HITACHI CHEMICAL CO LTD (JP) 2004-07-28 EP disclosed
US-20020151659-A1 Formed from 6,6'-bis(2-(4-fluorophenyl)-4- phenylquinoline) and 4,4'-(1,1,1,3,3,3-hexafluoro-2,2-propylidene)bisphenol and 2,2-bis((4-maleimidophenoxy)phenyl)propane; dielectrics HITACHI CHEMICAL CO., LTD. (JP) 2002-10-17 US disclosed
US-6462148-B1 RESIN COMPOSITION COMPRISING A POLYMER CONTAINING A QUINOLINE RING AND A THERMOSETTING RESIN, AN INSULATING MATERIAL CONSTITUTED BY SAID RESIN COMPOSITION AND AN ADHESIVE FILM, PARTICULARLY A RESIN FOR AN INTERLAYER INSULATION FILM HITACHI CHEMICAL CO., LTD. (JP) 2002-10-08 US disclosed
US-6404068-B1 (A) A THERMOPLASTIC RESIN, (B) AN EPOXY RESIN, (C) A COUPLING AGENT, (D) A POWDERY INORGANIC FILLER, (E) A POWDER HAVING RUBBER ELASTICITY AND (F) AN ORGANIC SOLVENT; LOW WATER VAPOR PERMEABILITY HITACHI CHEMICAL COMPANY, LTD. (JP) 2002-06-11 US disclosed
US-6297341-B1 SUPERIOR HEAT RESISTANCE AND FLEXIBILITY, DOW CORNING TORAY SILICONE COMPANY LTD (JP) 2001-10-02 US disclosed
EP-1114845-A1 PASTE COMPOSITION, AND PROTECTIVE FILM AND SEMICONDUCTOR DEVICE BOTH OBTAINED WITH THE SAME HITACHI CHEMICAL COMPANY, LTD. (JP) 2001-07-11 EP disclosed
US-6133394-A ACID CATALYTICALLY REACTING AN ORGANOCYCLOTRISILOXANE WITH AN ORGANODISILOXANE, HYDROSILATION OF END GROUPS WITH AN UNSATURATED EPOXY OR PHENOL COMPOUND REACTIVE WITH AN ORGANIC RESIN DOW CORNING TORAY SILICONE CO., LTD. (JP) 2000-10-17 US disclosed
US-6132852-A LAMINATE OF POLYMER CONDUCTOR AND DIELECTRIC HITACHI, LTD. (JP) 2000-10-17 US disclosed
EP-0933387-A1 Method for preparation of organofunctional pentasiloxane, organic resin modifier and organic resins Dow Corning Toray Silicone Company, Ltd. (JP) 1999-08-04 EP disclosed