SCHEMBL6902996

SCHEMBL6902996

NC(=O)c1cccc(C(=O)N2CCCCCCC2)c1

nearest known ligand 0.66

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.66
LMNA P02545 2/20 0.60
POLB P06746 1/20 0.60
ALDH1A1 P00352 5/20 0.59
GAA P10253 3/20 0.58
L3MBTL3 Q96JM7 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
SMN1; SMN2 Q16637 1/20 0.57
KDM4E B2RXH2 1/20 0.56
USP2 O75604 2/20 0.56
MEN1 O00255 1/20 0.55
HTT P42858 1/20 0.55
KMT2A Q03164 1/20 0.55
MAPK1 P28482 2/20 0.55
TP53 P04637 1/20 0.53
MAPT P10636 1/20 0.53
TSHR P16473 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL538600 1.00 HPGD (0.66) HPGDLMNAPOLBALDH1A1GAA
SCHEMBL28377650 1.00 HPGD (0.66) HPGDLMNAPOLBALDH1A1GAA
SCHEMBL180076 1.00 HPGD (0.66) HPGDLMNAPOLBALDH1A1GAA
SCHEMBL369227 1.00 HPGD (0.66) HPGDLMNAPOLBALDH1A1GAA
SCHEMBL367274 1.00 HPGD (0.66) HPGDLMNAPOLBALDH1A1GAA
SCHEMBL538527 1.00 HPGD (0.66) HPGDLMNAPOLBALDH1A1GAA
SCHEMBL472245 1.00 HPGD (0.66) HPGDLMNAPOLBALDH1A1GAA
SCHEMBL472260 1.00 HPGD (0.66) HPGDLMNAPOLBALDH1A1GAA
SCHEMBL367502 0.98 HPGD (0.65) HPGDLMNAPOLBALDH1A1GAA
Terephthalamide SCHEMBL198417 0.97 HPGD (0.62) HPGDLMNAPOLBALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0735082-B1 Polyphthalamide resin compositions SOLVAY ADVANCED POLYMERS LLC (US) 2004-05-26 EP disclosed
US-6306951-B1 TOUGHNESS, ELONGATION BP CORPORATION NORTH AMERICA INC. 2001-10-23 US disclosed
EP-0807665-B1 Flame retardant high temperature polyphthalamides having improved thermal stability BP AMOCO CORP (US) 2000-07-12 EP disclosed
US-5773500-A BROMINATED POLYSTYRENE WITH ANTIMONY COMPOUND AND MOLDING, CALCIUM OXIDE, MAGNESIUM OXIDE AND ZINC OXIDE AMOCO CORPORATION (US) 1998-06-30 US disclosed
EP-0812869-A2 Improved polyphthalamide composition AMOCO CORPORATION (US) 1997-12-17 EP disclosed
US-5665806-A MIXTURE WITH ALKALI METAL HALIDE, POTASSIUM IODIDE, AND COPPER IODIDE STABILIZER; HEAT RESISTANCE AMOCO CORPORATION (US) 1997-09-09 US disclosed
US-5585429-A CONTAINING LITHIUM HALIDE; REDUCED MELT VISCOSITY AMOCO CORPORATION (US) 1996-12-17 US disclosed
EP-0735082-A2 Polyphtalamide resin formulations AMOCO CORPORATION (US) 1996-10-02 EP disclosed
US-5436294-A Impact modifiers for improved ductility and rigidity AMOCO CORPORATION (US) 1995-07-25 US disclosed
US-5387645-A Synergistic blend of polyamide, functionalized polyolefin and functionalized styrene blocks and rubber blocks of ethylene, propylene, butylene and pentylene; maleic anhydride-modified AMOCO CORPORATION (US) 1995-02-07 US disclosed
EP-0477027-A2 Improved polyphthalamide composition AMOCO CORPORATION (US) 1992-03-25 EP disclosed