Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.65 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472245 | 0.98 | HPGD (0.66) | HPGDL3MBTL3L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL28377650 | 0.98 | HPGD (0.66) | HPGDL3MBTL3L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL367274 | 0.98 | HPGD (0.66) | HPGDL3MBTL3L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL538527 | 0.98 | HPGD (0.66) | HPGDL3MBTL3L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL472260 | 0.98 | HPGD (0.66) | HPGDL3MBTL3L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL6902996 | 0.98 | HPGD (0.66) | HPGDL3MBTL3L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL538600 | 0.98 | HPGD (0.66) | HPGDL3MBTL3L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL369227 | 0.98 | HPGD (0.66) | HPGDL3MBTL3L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL180076 | 0.98 | HPGD (0.66) | HPGDL3MBTL3L3MBTL1SMN1; SMN2LMNA | |
| Terephthalamide SCHEMBL198417 | 0.95 | HPGD (0.62) | HPGDL3MBTL3L3MBTL1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236795-B2 | IL-12 modulatory compounds | SYNTA PHARMACEUTICALS CORP. (US) | 2012-08-07 | — | — | US | claimed |
| US-20100256132-A1 | IL-12 MODULATORY COMPOUNDS | SYNTA PHARMACEUTICALS CORPORATION (US) | 2010-10-07 | — | — | US | claimed |
| US-7696202-B2 | IL-12 modulatory compounds | SYNTA PHARMACEUTICALS CORP. (US) | 2010-04-13 | — | — | US | claimed |
| EP-1819341-A2 | IL-12 MODULATORY COMPOUNDS | Synta Pharmaceuticals Corporation (US) | 2007-08-22 | — | — | EP | claimed |
| US-20060223996-A1 | IL-12 modulatory compounds | SYNTA PHARMACEUTICALS CORP. (US) | 2006-10-05 | — | — | US | claimed |
| WO-2006053227-A2 | IL-12 MODULATORY COMPOUNDS | SYNTA PHARMACEUTICALS CORP. (US) | 2006-05-18 | — | — | WO | claimed |
| EP-0411709-B1 | Polyamide composition | DSM NV (NL) | 1994-06-01 | — | — | EP | claimed |
| EP-0270146-B1 | COPOLYAMIDE AND A PROCESS FOR THE PREPARATION THEREOF | DSM N.V. (NL) | 1992-09-23 | — | — | EP | claimed |
| US-5084552-A | Tetramethylenediamine with adipic acid, terephthalic acid and isophthalic acid terpolyamide for moldings and films | STAMICARBON B.V. (NL) | 1992-01-28 | — | — | US | claimed |
| EP-0411709-A1 | Polyamide composition | DSM N.V. (NL) | 1991-02-06 | — | — | EP | claimed |
| EP-0270146-A1 | Copolyamide and a process for the preparation thereof | DSM N.V. (NL) | 1988-06-08 | — | — | EP | claimed |
| EP-0247203-A1 | POLYAMIDE PACKAGING MATERIAL | TEIJIN LIMITED (JP) | 1987-12-02 | — | — | EP | claimed |
| WO-1987002680-A2 | POLYAMIDE PACKAGING MATERIAL | TEIJIN LIMITED (JP) | 1987-05-07 | — | — | WO | claimed |
| JP-62106926-A | — | — | None | — | — | JP | disclosed |
| CN-112226081-B | Laser sensitization resin composition, preparation method and application thereof | 中国石油化工股份有限公司 | 2023-05-02 | — | — | CN | disclosed |
| US-11254082-B2 | Multi-layer tube | UBE INDUSTRIES, LTD. (JP) | 2022-02-22 | — | — | US | disclosed |
| JP-S62106926-A | POLYAMIDE PACKAGING MATERIAL | TEIJIN LTD | 1987-05-18 | — | — | JP | disclosed |
| WO-1987002680-A2 | POLYAMIDE PACKAGING MATERIAL | TEIJIN LIMITED (JP) | 1987-05-07 | — | — | WO | disclosed |
| WO-1987002680-A2 | POLYAMIDE PACKAGING MATERIAL | TEIJIN LIMITED (JP) | 1987-05-07 | — | — | WO | disclosed |
| EP-0219973-A2 | Impact resistant polyamide compositions | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1987-04-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223996-A1 | IL-12 modulatory compounds | IL2, IL4, IFNG | HPGD 146/4885L3MBTL3 4667/4885L3MBTL1 4697/4885 |
| US-20100256132-A1 | IL-12 MODULATORY COMPOUNDS | IL2, IL4, IFNG | HPGD 146/4885L3MBTL3 4667/4885L3MBTL1 4697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.