Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 4/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19809347 | 1.00 | GRM2 (0.41) | GRM2MMP2MMP3MMP9CYP2C9 | |
| SCHEMBL6903187 | 1.00 | GRM2 (0.41) | GRM2MMP2MMP3MMP9CYP2C9 | |
| SCHEMBL19809159 | 1.00 | GRM2 (0.41) | GRM2MMP2MMP3MMP9CYP2C9 | |
| SCHEMBL9288365 | 1.00 | GRM2 (0.41) | GRM2MMP2MMP3MMP9CYP2C9 | |
| SCHEMBL6931179 | 0.98 | GRM2 (0.40) | GRM2MMP2MMP3MMP9 | |
| SCHEMBL19809158 | 0.93 | GRM2 (0.39) | GRM2MMP2MMP3MMP9CYP2C9 | |
| SCHEMBL19809173 | 0.85 | CHRM2 (0.37) | — | |
| SCHEMBL28606146 | 0.80 | MMP2 (0.44) | GRM2MMP2MMP3MMP9 | |
| SCHEMBL4087910 | 0.80 | MMP2 (0.38) | GRM2MMP2MMP3MMP9 | |
| SCHEMBL9280922 | 0.77 | CHRM2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686483-B2 | REACTING AN OXIDIZER WITH AN OLEFIN IN PRESENCE OF KETONE | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION | 2004-02-03 | — | — | US | disclosed |
| EP-1021426-B1 | CATALYTIC ASYMMETRIC EPOXIDATION | UNIV COLORADO STATE RES FOUND (US) | 2003-09-17 | — | — | EP | disclosed |
| US-20020133031-A1 | Catalytic asymmetric epoxidation | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2002-09-19 | — | — | US | disclosed |
| US-6348608-B1 | ADDING OXIDIZING AGENT TO REACTION SOLUTION COMPRISING CHIRAL CYCLIC ENANTIOMERICALLY ENRICHED KETONE AND OLEFIN UNDER CONDITIONS EFFECTIVE TO GENERATE ENANTIOMERICALLY ENRICHED EPOXIDE, SEPARATING EPOXIDE FROM REACTION SOLUTION | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION | 2002-02-19 | — | — | US | disclosed |
| EP-1021426-A4 | CATALYTIC ASYMMETRIC EPOXIDATION | UNIV COLORADO STATE RES FOUND (US) | 2000-07-26 | — | — | EP | disclosed |
| EP-1021426-A1 | CATALYTIC ASYMMETRIC EPOXIDATION | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2000-07-26 | — | — | EP | disclosed |
| WO-1998015544-A1 | CATALYTIC ASYMMETRIC EPOXIDATION | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1998-04-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020133031-A1 | Catalytic asymmetric epoxidation | CBR1, AOX1, CBR3 | GRM2 3151/4885MMP2 2571/4885MMP3 3459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.