Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 15/20 | 0.76 |
| ▸ | DRD2 | P14416 | 14/20 | 0.76 |
| ▸ | DRD5 | P21918 | 13/20 | 0.73 |
| ▸ | DRD3 | P35462 | 11/20 | 0.73 |
| ▸ | DRD4 | P21917 | 9/20 | 0.73 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901150 | 0.96 | DRD1 (0.73) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL31634361 | 0.89 | DRD1 (0.69) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL11205264 | 0.89 | DRD1 (0.69) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL8408108 | 0.86 | — | — | |
| SCHEMBL31513871 | 0.85 | DRD1 (1.00) | DRD1DRD2DRD5DRD3DRD4 | |
| Ammonia Solution, Strong SCHEMBL21632258 | 0.84 | DRD2 (0.54) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL30672580 | 0.81 | — | — | |
| SCHEMBL21318766 | 0.81 | — | — | |
| SCHEMBL14317167 | 0.81 | DRD1 (0.61) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL217399 | 0.78 | KDM4E (0.59) | DRD1DRD2DRD5DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7411072-B2 | Tricyclic steroid hormone nuclear receptor modulators | ELI LILLY AND COMPANY (US) | 2008-08-12 | — | — | US | disclosed |
| US-6815481-B2 | FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-09 | — | — | US | disclosed |
| US-4448786-A | TREATMENT AND PREVENTION OF CALCIUM OXALATE KIDNEY STONES | MERCK & CO., INC. (US) | 1984-05-15 | — | — | US | disclosed |
| US-4349561-A | 4-Substituted-3-hydroxy-3-pyrroline-2,5-dione inhibitors of glycolic acid oxidase | MERCK & CO., INC. (US) | 1982-09-14 | — | — | US | disclosed |