SCHEMBL217399

SCHEMBL217399

Oc1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.59
NPC1 O15118 1/20 0.59
ALDH1A1 P00352 1/20 0.59
LMNA P02545 1/20 0.59
MAPT P10636 1/20 0.59
HPGD P15428 1/20 0.59
RAB9A P51151 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
SRD5A2 P31213 1/20 0.56
DRD2 P14416 9/20 0.55
DRD1 P21728 9/20 0.55
HSD17B1 P14061 1/20 0.55
DRD5 P21918 7/20 0.53
DRD3 P35462 7/20 0.53
DRD4 P21917 6/20 0.53
CYP1A2 P05177 2/20 0.53
CYP3A4 P08684 1/20 0.53
MAOA P21397 2/20 0.50
ADRA2A P08913 1/20 0.50
SLC6A2 P23975 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29373696 1.00 KDM4E (0.59) KDM4ENPC1ALDH1A1LMNAMAPT
SCHEMBL27482614 0.98 KDM4E (0.57) KDM4ENPC1ALDH1A1LMNAMAPT
SCHEMBL27527997 0.98 KDM4E (0.57) KDM4ENPC1ALDH1A1LMNAMAPT
SCHEMBL27482979 0.98 KDM4E (0.57) KDM4ENPC1ALDH1A1LMNAMAPT
SCHEMBL30680392 0.91 ALDH1A1 (0.53) KDM4ENPC1ALDH1A1LMNAMAPT
SCHEMBL29682646 0.91 ALDH1A1 (0.53) KDM4ENPC1ALDH1A1LMNAMAPT
SCHEMBL2763754 0.91 ALDH1A1 (0.53) KDM4ENPC1ALDH1A1LMNAMAPT
SCHEMBL788852 0.89 HSD17B1 (0.64) NPC1MAPTRAB9ADRD2DRD1
SCHEMBL29439100 0.89 HSD17B1 (0.64) NPC1MAPTRAB9ADRD2DRD1
SCHEMBL15676305 0.88 MAOA (0.67) KDM4ENPC1ALDH1A1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120059849-A Safflower pepper aromatic water and preparation method and application thereof 梅良屿 2025-05-30 CN claimed
CN-120028471-A Method for synchronously extracting and detecting 59 endocrine disruptors in amniotic fluid 天津大学温州安全(应急)研究院 2025-05-23 CN claimed
CN-119846104-A Detection method for multiple polycyclic aromatic hydrocarbon metabolites in urine 中国疾病预防控制中心环境与健康相关产品安全所 2025-04-18 CN claimed
CN-115656379-B Extraction method of phthalate and polycyclic aromatic hydrocarbon in blood 遵义医科大学 2025-03-25 CN claimed
CN-117929578-A Method for detecting hydroxy polycyclic aromatic hydrocarbon in urine and application thereof 河南省商业科学研究所有限责任公司 2024-04-26 CN claimed
CN-117310018-A Method for simultaneously detecting 16 hydroxyl polycyclic aromatic hydrocarbon substances in urine 中国测试技术研究院 2023-12-29 CN claimed
CN-116606275-A Preparation and application of indenocoumarin photosensitive protecting group 孙晓华 2023-08-18 CN claimed
CN-115326994-A Method and system for simultaneously analyzing multi-class smoke exposure biomarkers and using method 上海烟草集团有限责任公司 2022-11-11 CN claimed
CN-111163861-B Palladium-based acetylene selective hydrogenation catalysts enhanced with organic dopants 切弗朗菲利浦化学公司 2022-08-23 CN claimed
CN-111983053-B Solid phase extraction-liquid chromatography triple quadrupole mass spectrometry isotope dilution method for online determination of hydroxyl polycyclic aromatic hydrocarbons in urine 广东工业大学 2022-08-02 CN claimed
US-20170306504-A1 CORROSION INHIBITOR COMPOSITIONS AND METHODS OF USING SAME CHAMPIONX LLC 2017-10-26 US claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US claimed
EP-0698030-B1 PREPARATION OF FLUORO-COMPOUNDS RHODIA LIMITED (GB) 1999-03-03 EP claimed
US-5663030-A A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT XEROX CORPORATION (US) 1997-09-02 US claimed
US-4906549-A Positive-working photoresist composition with quinone diazide sulfonic acid ester and novolac made from m-cresol, p-cresol and aliphatic phenol with 2-6 carbon atoms TOKYO OHKA KOGYO CO., LTD. (JP) 1990-03-06 US claimed
US-4847178-A Positive photosensitive o-quinone diazide composition with benzotriazole carboxylic acid or alkyl ester TOKYO OHKA KOGYO CO., LTD. (JP) 1989-07-11 US claimed
EP-0113293-B1 LIQUID CRYSTALS FAMILY WITH A SMECTIC A PHASE, AND PROCESS FOR ITS PREPARATION THOMSON-CSF (FR) 1986-08-20 EP claimed
EP-0118685-A1 Propene derivatives and their use as plant growth inhibitors DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1984-09-19 EP claimed
EP-0117412-A1 Propene derivatives and their use as plant growth inhibitors DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1984-09-05 EP claimed