Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 8/20 | 0.38 |
| ▸ | HTR1B | P28222 | 6/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6907139 | 0.80 | TAAR1 (0.35) | HTR1DHTR1BADRA2AADRA2BADRA2C | |
| SCHEMBL6906006 | 0.75 | POLB (0.41) | HTR1DHTR1BADRA2AADRA2BADRA2C | |
| SCHEMBL6905892 | 0.74 | PON1 (0.36) | CYP2D6ELANECD69CYP1A2CYP2C9 | |
| SCHEMBL6900216 | 0.65 | POLB (0.35) | HTR1DHTR1BADRA2AADRA2BADRA2C | |
| SCHEMBL6901135 | 0.64 | POLB (0.41) | HTR1DHTR1BADRA2AADRA2BADRA2C | |
| SCHEMBL6906560 | 0.63 | ELANE (0.37) | HTR1DHTR1BCYP2D6TSHRHTR2A | |
| SCHEMBL1655430 | 0.62 | GABRA1 (0.55) | HTR1DHTR1BADRA2AADRA2BADRA2C | |
| SCHEMBL1316919 | 0.62 | HTR1D (0.48) | HTR1DHTR1BLMNATP53TSHR | |
| SCHEMBL316288 | 0.62 | TSHR (0.50) | HTR1DHTR1BADRA2AADRA2BADRA2C | |
| SCHEMBL21518797 | 0.62 | CYP1A2 (0.36) | CYP2D6TSHRMAPK1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815481-B2 | FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-09 | — | — | US | disclosed |
| US-20020032256-A1 | Polybutadiene composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-03-14 | — | — | US | disclosed |