Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTR1D | P28221 | 7/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CD69 | Q07108 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 5/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6900216 | 0.87 | POLB (0.35) | POLBHTR1DELANECD69TSHR | |
| SCHEMBL6901135 | 0.83 | POLB (0.41) | POLBHTR1DELANECD69TSHR | |
| SCHEMBL6907158 | 0.77 | POLB (0.34) | POLBHTR1DELANECD69TSHR | |
| SCHEMBL6903704 | 0.75 | HTR1D (0.38) | POLBHTR1DELANECD69TSHR | |
| SCHEMBL6905892 | 0.75 | PON1 (0.36) | ELANECD69CYP2D6TLR4CD14 | |
| SCHEMBL6907139 | 0.73 | TAAR1 (0.35) | POLBHTR1DTSHRHTR1BADRA2A | |
| SCHEMBL19739528 | 0.71 | MAOA (0.33) | POLBHTR1DHTR1BMAPT | |
| SCHEMBL18261204 | 0.71 | ALDH1A1 (0.37) | POLBHTR1DTSHRHTR1BADRA2A | |
| SCHEMBL19398835 | 0.69 | POLB (0.33) | POLBHTR1DELANECD69GABRA1 | |
| SCHEMBL3271525 | 0.69 | BCL2L1 (0.42) | POLBELANECD69GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815481-B2 | FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-09 | — | — | US | disclosed |