Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | EIF4A3 | P38919 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | DAO | P14920 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30797370 | 0.80 | HPGD (0.47) | HPGDHSD17B10ALDH1A1MEN1USP2 | |
| SCHEMBL27085692 | 0.80 | HPGD (0.47) | HPGDHSD17B10ALDH1A1MEN1USP2 | |
| SCHEMBL23850060 | 0.79 | HPGD (0.49) | HPGDHSD17B10ALDH1A1MEN1USP2 | |
| SCHEMBL30961886 | 0.79 | EGFR (0.38) | BAZ1ATDO2 | |
| SCHEMBL11219318 | 0.78 | HSD17B10 (0.63) | HPGDHSD17B10ALDH1A1MEN1USP2 | |
| SCHEMBL1808544 | 0.76 | EGFR (0.38) | TDO2 | |
| SCHEMBL3598248 | 0.75 | HPGD (0.62) | HPGDHSD17B10ALDH1A1MEN1USP2 | |
| SCHEMBL8630444 | 0.74 | HSD17B10 (0.60) | HPGDHSD17B10ALDH1A1MEN1USP2 | |
| SCHEMBL11117589 | 0.73 | EGFR (0.34) | TDO2 | |
| SCHEMBL30961759 | 0.72 | EGFR (0.45) | TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250090658-A1 | POLYMER ADJUVANT | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2025-03-20 | — | — | US | disclosed |
| US-20210000934-A1 | POLYMER ADJUVANT | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2021-01-07 | — | — | US | disclosed |
| US-20170304420-A1 | POLYMER ADJUVANT | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2017-10-26 | — | — | US | disclosed |
| EP-3215189-A1 | POLYMER ADJUVANT | Oxford University Innovation Limited (GB) | 2017-09-13 | — | — | EP | disclosed |
| WO-2016055812-A1 | POLYMER ADJUVANT | ISIS INNOVATION LIMITED (GB) | 2016-04-14 | — | — | WO | disclosed |
| US-6774236-B1 | METHYLBENZENEACETIC ACID ESTER DERIVATIVES AS CHEMICAL INTERMEDIATES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-08-10 | — | — | US | disclosed |
| US-5952498-A | SYNTHESIZING THE CHEMICAL INTERMEDIATES FOR ANTIATHEROSCLEROTICALLY ACTIVE DRUG | BAYER AKTIENGESELLSCHAFT (DE) | 1999-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210000934-A1 | POLYMER ADJUVANT | TLR3, TLR9, TLR1 | HPGD 2189/4885HSD17B10 3898/4885ALDH1A1 3788/4885 |
| US-20170304420-A1 | POLYMER ADJUVANT | TLR3, TLR9, TLR1 | HPGD 2189/4885HSD17B10 3898/4885ALDH1A1 3788/4885 |
| US-20250090658-A1 | POLYMER ADJUVANT | TLR3, TLR9, TLR1 | HPGD 2189/4885HSD17B10 3898/4885ALDH1A1 3788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.