Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 5/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26270570 | 1.00 | TDP1 (0.52) | TDP1MAPTSPHK1FAAHCNR1 | |
| SCHEMBL31680382 | 0.98 | TDP1 (0.53) | TDP1MAPTSPHK1FAAHCNR1 | |
| SCHEMBL2266461 | 0.94 | TDP1 (0.55) | TDP1MAPTSPHK1FAAHCNR1 | |
| SCHEMBL2268828 | 0.94 | TDP1 (0.55) | TDP1MAPTSPHK1FAAHCNR1 | |
| SCHEMBL2266778 | 0.94 | TDP1 (0.55) | TDP1MAPTSPHK1FAAHCNR1 | |
| SCHEMBL7941774 | 0.91 | TDP1 (0.55) | TDP1MAPTSPHK1FAAHCNR1 | |
| SCHEMBL7940951 | 0.88 | TDP1 (0.57) | TDP1MAPTSPHK1FAAHCNR1 | |
| SCHEMBL7943965 | 0.88 | TDP1 (0.57) | TDP1MAPTSPHK1FAAHCNR1 | |
| SCHEMBL6420891 | 0.86 | GPR84 (0.46) | SPHK1FAAHCNR1CNR2GPR84 | |
| SCHEMBL29259717 | 0.86 | GPR84 (0.46) | SPHK1FAAHCNR1CNR2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237408-B1 | POUR-ON FORMULATIONS | LILLY CO ELI (US) | 2004-02-18 | — | — | EP | claimed |