Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.84 |
| ▸ | DRD1 | P21728 | 2/20 | 0.58 |
| ▸ | DRD4 | P21917 | 2/20 | 0.58 |
| ▸ | DRD5 | P21918 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | MAOA | P21397 | 5/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13456132 | 1.00 | MAPT (0.84) | MAPTCYP3A4DRD1DRD4DRD5 | |
| SCHEMBL2594537 | 0.92 | MAPT (0.68) | MAPTCYP3A4DRD1DRD4DRD5 | |
| SCHEMBL29924708 | 0.92 | MAPT (0.68) | MAPTCYP3A4DRD1DRD4DRD5 | |
| SCHEMBL14481557 | 0.92 | MAPT (0.68) | MAPTCYP3A4DRD1DRD4DRD5 | |
| SCHEMBL4571013 | 0.92 | CYP3A4 (1.00) | MAPTCYP3A4DRD1DRD4DRD5 | |
| SCHEMBL2138785 | 0.92 | CYP3A4 (1.00) | MAPTCYP3A4DRD1DRD4DRD5 | |
| SCHEMBL22953335 | 0.92 | CYP3A4 (1.00) | MAPTCYP3A4DRD1DRD4DRD5 | |
| SCHEMBL29394312 | 0.92 | CYP3A4 (1.00) | MAPTCYP3A4DRD1DRD4DRD5 | |
| SCHEMBL2241521 | 0.84 | GAA (0.61) | MAPTCYP3A4DRD1DRD4DRD5 | |
| SCHEMBL59900 | 0.81 | MAPT (0.62) | MAPTCYP3A4DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815481-B2 | FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-09 | — | — | US | disclosed |