SCHEMBL4571013

SCHEMBL4571013

COc1cc2c(cc1OC)Cc1cc(OC)c(OC)cc1Cc1cc(OC)c(OC)cc1C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 1.00
MAPT P10636 2/20 1.00
DRD1 P21728 2/20 0.53
DRD4 P21917 2/20 0.53
DRD5 P21918 2/20 0.53
GAA P10253 2/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
DRD2 P14416 1/20 0.47
DRD3 P35462 1/20 0.47
KDM4E B2RXH2 5/20 0.46
MAOA P21397 5/20 0.46
CHRNA7 P36544 2/20 0.46
MAOB P27338 2/20 0.46
SLC6A4 P31645 1/20 0.46
ALDH1A1 P00352 4/20 0.43
GLA P06280 2/20 0.43
ACHE P22303 1/20 0.43
BRD4 O60885 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2138785 1.00 CYP3A4 (1.00) CYP3A4MAPTDRD1DRD4DRD5
SCHEMBL29394312 1.00 CYP3A4 (1.00) CYP3A4MAPTDRD1DRD4DRD5
SCHEMBL22953335 1.00 CYP3A4 (1.00) CYP3A4MAPTDRD1DRD4DRD5
SCHEMBL13456132 0.92 MAPT (0.84) CYP3A4MAPTDRD1DRD4DRD5
SCHEMBL6904036 0.92 MAPT (0.84) CYP3A4MAPTDRD1DRD4DRD5
SCHEMBL25591699 0.88 CYP3A4 (0.78) CYP3A4MAPTDRD1DRD4DRD5
SCHEMBL29460958 0.88 CYP3A4 (0.78) CYP3A4MAPTDRD1DRD4DRD5
SCHEMBL13508341 0.87 MAPT (0.76) CYP3A4MAPTDRD1DRD4DRD5
SCHEMBL7981630 0.86 MAPT (0.75) CYP3A4MAPTDRD1DRD4DRD5
SCHEMBL12595457 0.84 MAPT (0.71) CYP3A4MAPTDRD1DRD4DRD5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11401356-B2 Olefin polymerization catalyst comprising cyclotriveratrylene and derivatives thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2022-08-02 US disclosed
US-20200181296-A1 OLEFIN POLYMERIZATION CATALYST COMPRISING CYCLOTRIVERATRYLENE AND DERIVATIVES THEREOF BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2020-06-11 US disclosed
EP-3656754-A1 OLEFIN POLYMERIZATION CATALYST COMPRISING CYCLOTRIVERATRYLENE AND DERIVATIVES THEREOF China Petroleum&Chemical Corporation (CN) 2020-05-27 EP disclosed
US-20170184531-A1 GAS SENSOR ARRAY AND METHOD NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2017-06-29 US disclosed
US-9045582-B2 Cross-linked rubbery polyurethane-ether membranes for separations UOP LLC (US) 2015-06-02 US disclosed
US-9045582-B2 Cross-linked rubbery polyurethane-ether membranes for separations UOP LLC (US) 2015-06-02 US disclosed
US-20150114224-A1 CROSS-LINKED RUBBERY POLYURETHANE-ETHER MEMBRANES FOR SEPARATIONS UOP LLC (US) 2015-04-30 US disclosed
US-20150114224-A1 CROSS-LINKED RUBBERY POLYURETHANE-ETHER MEMBRANES FOR SEPARATIONS UOP LLC (US) 2015-04-30 US disclosed
US-8173803-B2 Supramolecular scaffolds and methods of making the same LOYOLA UNIVERSITY OF CHICAGO (US) 2012-05-08 US disclosed
US-8173803-B2 Supramolecular scaffolds and methods of making the same LOYOLA UNIVERSITY OF CHICAGO (US) 2012-05-08 US disclosed
US-20100051554-A1 MOLECULAR BASKET COATED MICRO PARTICLES KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2010-03-04 US disclosed
US-20100041880-A1 Supramolecular Scaffolds and Methods of Making the Same LOYOLA UNIVERSITY OF CHICAGO (US) 2010-02-18 US disclosed
US-20100041880-A1 Supramolecular Scaffolds and Methods of Making the Same LOYOLA UNIVERSITY OF CHICAGO (US) 2010-02-18 US disclosed
EP-1099743-B1 Photochromic plastic article RODENSTOCK GMBH (DE) 2004-11-10 EP disclosed
EP-1099743-A1 Photochromic plastic article Optische Werke G. Rodenstock (DE) 2001-05-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200181296-A1 OLEFIN POLYMERIZATION CATALYST COMPRISING CYCLOTRIVERATRYLENE AND DERIVATIVES THEREOF CCNT1, CHRM1, CHRM2 CYP3A4 112/4885MAPT 352/4885DRD1 999/4885
US-20100041880-A1 Supramolecular Scaffolds and Methods of Making the Same BLM, TBXAS1, TOP2B CYP3A4 175/4885MAPT 2040/4885DRD1 4183/4885
US-11401356-B2 Olefin polymerization catalyst comprising cyclotriveratrylene and derivatives thereof CCNT1, CHRM1, CHRM2 CYP3A4 112/4885MAPT 352/4885DRD1 999/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.