SCHEMBL690409

SCHEMBL690409

Brc1nccnc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21737309 0.75
SCHEMBL29913086 0.75
SCHEMBL30032094 0.75
SCHEMBL31094383 0.75
SCHEMBL557517 0.75
SCHEMBL22984840 0.75
SCHEMBL30591980 0.75
SCHEMBL10983965 0.73
SCHEMBL22440551 0.71
SCHEMBL10986252 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119009136-A Pyrazinyl eutectic electrolyte with wide electrochemical stability window, and preparation method and application thereof 中国科学院长春应用化学研究所 2024-11-22 CN claimed
CN-118307545-A Organic electronic transmission material, preparation method thereof and electroluminescent device 季华实验室 2024-07-09 CN claimed
CN-105622526-A Preparation method of 2-aminopyrazine derivatives UNIV HUBEI TECHNOLOGY 2016-06-01 CN claimed
EP-4747241-A1 BENZIMIDAZOLE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-05-27 EP disclosed
WO-2026103873-A1 HETEROCYCLIC COMPOUND AND PHARMACEUTICAL USE THEREOF 杭州百新生物医药科技有限公司 2026-05-21 WO disclosed
US-12534462-B2 Substituted heteroaryls as thermally assisted delayed fluorescent materials ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2026-01-27 US disclosed
US-12497382-B2 GLP-1R modulating compounds GILEAD SCIENCES, INC. (US) 2025-12-16 US disclosed
US-12486259-B2 FXR agonist having pyrazine structure, and preparation method and use JIANGSU TASLY DIYI PHARMACEUTICAL CO., LTD. (CN) 2025-12-02 US disclosed
EP-4634178-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES Syngenta Crop Protection AG (CH) 2025-10-22 EP disclosed
US-12331056-B2 SHP2 phosphatase inhibitors and methods of use thereof RELAY THERAPEUTICS, INC. (US) 2025-06-17 US disclosed
CN-119874674-A GLP-1R modulating compounds 吉利德科学公司 2025-04-25 CN disclosed
WO-2005049546-A1 HALOGENATED BISDIARYLAMINOPOLYCYLIC AROMATIC COMPOUNDS AND POLYMERS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-06-02 WO disclosed
WO-2004113327-A1 EPOXY COMPOUND AND CURED EPOXY RESIN PRODUCT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-29 WO disclosed
EP-1482940-A2 PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE Pharmacia Corporation (US) 2004-12-08 EP disclosed
CN-1140176-C Selective herbicides based on arylsulphonylaminocarbonyltriazolinones 2004-03-03 CN disclosed
WO-2003028729-A2 PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE PHARMACIA CORPORATION (US) 2003-04-10 WO disclosed
CN-1238663-A Selective herbicides based on arylsulphonylaminocarbonyltriazolinones BAYER AG (DE) 1999-12-15 CN disclosed
EP-0470668-A1 A process for preparing enantiomers of compounds having muscarinic activity MERCK SHARP &amp; DOHME LTD. (GB) 1992-02-12 EP disclosed
US-4492700-A 3-Halo-2-thiopyrazines as antimicrobial agents MERCK & CO., INC. (US) 1985-01-08 US disclosed
US-3987044-A SEPARATION OF 2,3-DIAMINO-DIHALOPYRAZINES FROM MIXTURES AS NOVEL ASSOCIATION PRODUCTS WITH CERTAIN KETONES THE DOW CHEMICAL COMPANY (US) 1976-10-19 US disclosed