⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29913086 | 1.00 | — | — | |
| SCHEMBL29985108 | 0.75 | — | — | |
| SCHEMBL690409 | 0.75 | — | — | |
| SCHEMBL1024624 | 0.75 | — | — | |
| SCHEMBL29457483 | 0.65 | — | — | |
| SCHEMBL274632 | 0.65 | — | — | |
| SCHEMBL41047 | 0.65 | — | — | |
| SCHEMBL6711366 | 0.63 | — | — | |
| SCHEMBL20551999 | 0.63 | — | — | |
| SCHEMBL30398249 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107056789-B | With substitution pyrazine and imidazole derivative, preparation and its application in medicine | 陈剑 | 2019-03-29 | — | — | CN | claimed |
| CN-107056789-A | With substitution pyrazine and imidazole derivative, it is prepared and its in application pharmaceutically | 陈剑 | 2017-08-18 | — | — | CN | claimed |
| CN-104496917-A | Synthesis method of Favipiravir | NANJING HUAWE MEDICAL TECHNOLOGY DEV CO LTD | 2015-04-08 | — | — | CN | claimed |
| EP-4720058-A2 | BIFUNCTIONAL DEGRADERS AND USES THEREOF | Casma Therapeutics, Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| US-12565496-B2 | Substituted 1H-pyrrolo[3,2-b]pyridine compounds and methods of use thereof | BAYER AKTIENGESELLSCHAFT (DE) | 2026-03-03 | — | — | US | disclosed |
| US-20250388601-A1 | Compounds, Compositions and Methods | DENALI THERAPEUTICS INC. (US) | 2025-12-25 | — | — | US | disclosed |
| US-20250332155-A1 | SUBSTITUTED TETRAHYDROQUINOLINONE COMPOUNDS AS ROR GAMMA MODULATORS | AURIGENE ONCOLOGY LTD (IN) | 2025-10-30 | — | — | US | disclosed |
| US-20250304537-A1 | HETEROARENES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME | REPARE THERAPEUTICS INC. (CA) | 2025-10-02 | — | — | US | disclosed |
| US-12377088-B2 | Substituted tetrahydroquinolinone compounds as ROR gamma modulators | AURIGENE ONCOLOGY LIMITED (IN) | 2025-08-05 | — | — | US | disclosed |
| US-12365695-B2 | Fused ring heteroaryl compounds as RIPK1 inhibitors | BISICHEM CO., LTD. (KR) | 2025-07-22 | — | — | US | disclosed |
| US-12358928-B2 | Compounds, compositions and methods | DENALI THERAPEUTICS INC. (US) | 2025-07-15 | — | — | US | disclosed |
| CN-1272328-C | Pyrazine based inhibitors of glycogen synthase kinase 3 | CHIRON CORP (US) | 2006-08-30 | — | — | CN | disclosed |
| WO-2006086545-A2 | METHOD TO IDENTIFY NOVEL THERAPEUTICS | DESIMONE ROBERT W (US) | 2006-08-17 | — | — | WO | disclosed |
| CN-1668619-A | Imidazo [1, 2-a ] pyrazin-8-ylamines, methods of making and methods of use thereof | CELLULAR GENOMICS INC (US) | 2005-09-14 | — | — | CN | disclosed |
| CN-1639132-A | N-pyrazinyl-phenylsulphonamides and their use in the treatment of chemokine mediated diseases | ASTRAZENECA AB (SE) | 2005-07-13 | — | — | CN | disclosed |
| US-20040034225-A1 | Aryl-substituted n, n-heterocyclic compounds, method for their preparationand their use in therapeutics and diagnostics | UNIVERSITY CATHOLIQUE DE LOUVAIN (BE) | 2004-02-19 | — | — | US | disclosed |
| CN-1434807-A | Pyrazine based inhibitors of glycogen synthase kinase 3 | CHIRON CORP (US) | 2003-08-06 | — | — | CN | disclosed |
| EP-1292580-A1 | PYRAZINE AND IMIDAZOPYRAZINE DERIVATIVES AS ANTIOXIDANTS | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2003-03-19 | — | — | EP | disclosed |
| WO-2001087853-A1 | ARYL-SUBSTITUTED N,N-HETEROCYCLIC COMPOUNDS, METHOD FOR THEIR PREPARATION AND THEIR USE IN THERAPEUTICS AND DIAGNOSTICS | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2001-11-22 | — | — | WO | disclosed |
| JP-2001089460-A | PRODUCTION PROCESS FOR 2-AMINOBROMOPIPERAZINES | KOEI CHEM CO LTD | 2001-04-03 | — | — | JP | disclosed |