⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL557517 | 1.00 | — | — | |
| SCHEMBL29985108 | 0.75 | — | — | |
| SCHEMBL690409 | 0.75 | — | — | |
| SCHEMBL1024624 | 0.75 | — | — | |
| SCHEMBL29457483 | 0.65 | — | — | |
| SCHEMBL274632 | 0.65 | — | — | |
| SCHEMBL41047 | 0.65 | — | — | |
| SCHEMBL6711366 | 0.63 | — | — | |
| SCHEMBL20551999 | 0.63 | — | — | |
| SCHEMBL30398249 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120058702-A | Heterocyclic TEAD inhibitors | 武汉人福创新药物研发中心有限公司 | 2025-05-30 | — | — | CN | disclosed |
| EP-4329881-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-03-06 | — | — | EP | disclosed |
| WO-2022232383-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2022-11-03 | — | — | WO | disclosed |