Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.38 |
| ▸ | PPARG | P37231 | 5/20 | 0.36 |
| ▸ | PPARA | Q07869 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PTPRF | P10586 | 1/20 | 0.33 |
| ▸ | PTPRA | P18433 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3971665 | 0.87 | PTPN1 (0.45) | PTPN1PPARGPPARALMNAPTGER4 | |
| SCHEMBL3976050 | 0.86 | LMNA (0.46) | PTPN1PPARGPPARALMNAPTGER4 | |
| SCHEMBL3973021 | 0.83 | PPARG (0.47) | PPARGPPARAPPARD | |
| SCHEMBL11993095 | 0.79 | LMNA (0.47) | PTPN1PPARGPPARALMNAPTGER4 | |
| SCHEMBL11992997 | 0.76 | PPARG (0.43) | PPARGPPARA | |
| SCHEMBL6903473 | 0.75 | PPARG (0.44) | PTPN1PPARGPPARAPPARD | |
| SCHEMBL3968405 | 0.74 | PPARG (0.48) | PTPN1PPARGPPARALMNAPPARD | |
| SCHEMBL3976202 | 0.74 | PPARG (0.51) | PTPN1PPARGPPARAPPARD | |
| SCHEMBL11993021 | 0.74 | PPARG (0.51) | PTPN1PPARGPPARAPPARD | |
| SCHEMBL6904184 | 0.74 | KDM4E (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412326-A1 | BUTYRIC ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003011819-A1 | BUTYRIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2003-02-13 | — | — | WO | disclosed |