Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28327687 | 0.78 | NPC1 (0.43) | ALDH1A1MAPTKMT2ARAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL28426860 | 0.76 | TP53 (0.45) | ALDH1A1MAPTKMT2ARAB9AKDM4E | |
| SCHEMBL988218 | 0.72 | KMT2A (0.50) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL8213737 | 0.71 | TLR8 (0.49) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL9006267 | 0.71 | MAP4K4 (0.46) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL1115863 | 0.70 | ALDH1A1 (0.49) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL27812919 | 0.70 | ALDH1A1 (0.42) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL28237515 | 0.70 | KMT2A (0.42) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL6535908 | 0.70 | TLR8 (0.48) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL29034746 | 0.69 | ALDH1A1 (0.42) | ALDH1A1HPGDMAPTGLAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6737424-B2 | THERAPY FOR NERVOUS SYSTEM DISORDERS | ZENECA LTD. (GB) | 2004-05-18 | — | — | US | disclosed |
| US-20010007869-A1 | ALPHA-SUBSTITTUTED PYRIDAZINO QUINOLINE COMPOUNDS | SYNGENTA LIMITED (GB) | 2001-07-12 | — | — | US | disclosed |
| EP-0736531-A1 | Alpha-substituted pyridazino quinoline compounds | ZENECA LIMITED (GB) | 1996-10-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010007869-A1 | ALPHA-SUBSTITTUTED PYRIDAZINO QUINOLINE COMPOUNDS | CBR3, CHRNA1, CBR1 | ALDH1A1 1307/4885HPGD 1548/4885MAPT 4556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.