SCHEMBL6904210

SCHEMBL6904210

CS(=O)(=O)OC(c1ccccc1)(c1ccccc1)c1ccc(F)c(F)c1F

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA5A P35218 1/20 0.32
CA9 Q16790 1/20 0.32
KIF11 P52732 1/20 0.31
KCNN4 O15554 3/20 0.31
NR3C2 P08235 1/20 0.30
ALDH1A1 P00352 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28381845 0.68 KCNN4 (0.41) CA1CA2CA5ACA9KIF11
SCHEMBL30097456 0.67 CES1 (0.38) KIF11KCNN4ALDH1A1ALOX15
SCHEMBL29101509 0.66 CYP3A4 (0.41) KCNN4ALDH1A1ALOX15
SCHEMBL8318529 0.65 NR3C2 (0.43) CA1CA2CA5ACA9KCNN4
SCHEMBL4160700 0.65 KCNN4 (0.37) KIF11KCNN4ALDH1A1ALOX15
SCHEMBL15754961 0.64 CES2 (0.39) CA1CA2CA9KIF11
SCHEMBL2608417 0.64 CES2 (0.36) CA2ALDH1A1ALOX15
SCHEMBL5873337 0.63 CES1 (0.39) CA1CA2CA5ACA9KIF11
SCHEMBL5489283 0.62 CES2 (0.34)
SCHEMBL1194671 0.62 CES2 (0.35) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6794329-B2 REACTION PRODUCT OF LEWIS ACID AND SULFONATE NOVA CHEMICALS (INTERNATIONAL) S. A. (CH) 2004-09-21 US disclosed
EP-1451229-A1 CATALYST ACTIVATOR FOR POLYMERIZATION CATALYST Nova Chemicals (International) S.A. (CH) 2004-09-01 EP disclosed
US-20030144435-A1 Reaction product of lewis acid and sulfonate NOVA CHEMICALS (INTERNATIONAL) S.A. 2003-07-31 US disclosed
WO-2003054033-A1 CATALYST ACTIVATOR FOR POLYMERIZATION CATALYST NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2003-07-03 WO disclosed