Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.76 |
| ▸ | TYR | P14679 | 1/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 6/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | ESRRG | P62508 | 2/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL197202 | 0.87 | MEN1 (0.62) | LMNATYRPOLBMEN1KMT2A | |
| SCHEMBL19157 | 0.87 | LMNA (1.00) | LMNATYRMEN1KMT2AESR1 | |
| SCHEMBL25039118 | 0.86 | MEN1 (0.56) | LMNATYRPOLBMEN1KMT2A | |
| SCHEMBL4745386 | 0.86 | ESR1 (0.76) | LMNATYRPOLBMEN1KMT2A | |
| SCHEMBL3400553 | 0.86 | ESR1 (0.64) | LMNATYRPOLBMEN1KMT2A | |
| SCHEMBL11671791 | 0.85 | LMNA (0.52) | LMNATYRPOLBMEN1KMT2A | |
| SCHEMBL13149703 | 0.85 | LMNA (0.52) | LMNATYRPOLBMEN1KMT2A | |
| SCHEMBL13149639 | 0.85 | LMNA (0.52) | LMNATYRPOLBMEN1KMT2A | |
| Fluoride SCHEMBL8897268 | 0.85 | LMNA (0.94) | LMNATYRMEN1KMT2AESR1 | |
| Hydrogen Sulfide SCHEMBL1975873 | 0.85 | LMNA (0.94) | LMNATYRMEN1KMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6753364-B1 | BLEND WITH ORGANOPHOSPHONATE AMINE; MECHANICAL PROPERTIES, HEAT RESISTANCE, LOW-JUICING | BAYER AKTIENGESELLSCHAFT (DE) | 2004-06-22 | — | — | US | disclosed |