SCHEMBL5166701

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30342268	0.93	PPARA (0.56)	PPARAALOX15IGF1RKAT8KDM4E
	SCHEMBL10067474	0.93	PPARA (0.56)	PPARAALOX15IGF1RKAT8KDM4E
	SCHEMBL21034795	0.91	ALOX15 (0.52)	NPC1MAPK1RAB9AHPGDHTT
	SCHEMBL21034788	0.91	ALOX15 (0.57)	NPC1MAPK1RAB9AHPGDHTT
	SCHEMBL5167973	0.89	CNR1 (0.55)	NPC1MAPK1RAB9AHPGDHTT
	SCHEMBL21002247	0.89	ALOX15 (0.55)	PPARAALOX15IGF1RKAT8SMN1; SMN2
	SCHEMBL21034647	0.87	ALDH1A1 (0.52)	MAPK1HPGDHTTNPSR1ALOX15
	SCHEMBL29612324	0.86	HTT (0.52)	NPC1MAPK1RAB9AHPGDHTT
	SCHEMBL673963	0.86	HTT (0.52)	NPC1MAPK1RAB9AHPGDHTT
	Methane SCHEMBL27924017	0.84	HTT (0.50)	NPC1MAPK1RAB9AHPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.