Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL714587 | 0.78 | CYP11B1 (0.33) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL968804 | 0.78 | CYP11B1 (0.33) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL392658 | 0.78 | CYP11B1 (0.33) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL29790383 | 0.78 | CYP11B1 (0.33) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL27448383 | 0.75 | ALDH1A1 (0.33) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL5872672 | 0.74 | CYP19A1 (0.30) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL7940146 | 0.73 | ALDH1A1 (0.32) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL1539598 | 0.73 | CYP11B1 (0.35) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL1681583 | 0.72 | CYP11B1 (0.34) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL8673364 | 0.72 | ALDH1A1 (0.36) | CYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6790917-B2 | POLYMERIZING A VINYL COMPOUND IN PRESENCE OF A CATALYST OBTAINED BY COMBINING ORGANOTRANSITION METAL COMPOUND, AN ALUMINUM COMPUND OR ALUMOXANE AND A BORON COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-09-14 | — | — | US | disclosed |
| US-20020198340-A1 | Process for producing vinyl compound polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-12-26 | — | — | US | disclosed |