Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | TACR2 | P21452 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6904301 | 0.96 | HSD11B1 (0.32) | HSD11B1CYP3A4MEN1MAPTKMT2A | |
| SCHEMBL6902981 | 0.92 | S1PR1 (0.31) | ALDH1A1MEN1MAPTKMT2AS1PR1 | |
| SCHEMBL6901081 | 0.87 | KDM4E (0.32) | KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6897842 | 0.85 | RARB (0.33) | HSD17B10TSHRRARBSLC6A2SLC6A4 | |
| SCHEMBL6903792 | 0.83 | ALDH1A1 (0.32) | HSD17B10SLC6A2SLC6A4ADORA3SLC6A3 | |
| Hydrochloric Acid SCHEMBL6903351 | 0.81 | HSD11B1 (0.32) | HSD11B1 | |
| SCHEMBL6903054 | 0.80 | MAPT (0.30) | HSD17B10TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL6900000 | 0.80 | — | — | |
| SCHEMBL6897836 | 0.79 | BRD4 (0.33) | LMNATP53RAB9ASMN1; SMN2S1PR1 | |
| SCHEMBL6902623 | 0.79 | BRD4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033371-B1 | Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2004-01-28 | — | — | EP | claimed |