Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2457565 | 0.75 | KMT2A (0.47) | MEN1KMT2ANPC1LMNAHPGD | |
| SCHEMBL2457562 | 0.75 | KMT2A (0.47) | MEN1KMT2ANPC1LMNAHPGD | |
| SCHEMBL8768148 | 0.73 | TDP1 (0.50) | MEN1KMT2ALMNAALOX12NFKB1 | |
| SCHEMBL7209286 | 0.72 | KDM4E (0.55) | KMT2ALMNAHPGDNFKB1RAB9A | |
| SCHEMBL6074113 | 0.72 | ESR1 (0.55) | — | |
| SCHEMBL6905265 | 0.69 | HDAC1 (0.58) | LMNA | |
| SCHEMBL11267446 | 0.69 | TDP1 (0.42) | MEN1KMT2ALMNAALOX12RAB9A | |
| SCHEMBL7003804 | 0.66 | KDM4E (0.50) | MEN1KMT2ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL6904774 | 0.66 | TDP1 (0.45) | MEN1KMT2ALMNANFKB1NFKB2 | |
| SCHEMBL6904753 | 0.65 | TDP1 (0.44) | LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417169-A2 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | Bristol-Myers Squibb Pharma Company (US) | 2004-05-12 | — | — | EP | claimed |
| WO-2003016270-A2 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2003-02-27 | — | — | WO | claimed |