Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 8/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768148 | 0.90 | TDP1 (0.50) | TDP1L3MBTL1LMNAHSD17B10MAPT | |
| SCHEMBL9451160 | 0.83 | CA2 (0.53) | CNR1CNR2ESR1LMNAHSD17B10 | |
| SCHEMBL9661912 | 0.80 | ESR1 (0.47) | ESR1LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL19639015 | 0.80 | CNR1 (0.40) | TDP1L3MBTL1IDO1TDO2CNR1 | |
| SCHEMBL4543424 | 0.78 | ESR1 (0.59) | ESR1LMNAMAPTCYP3A4CYP2D6 | |
| SCHEMBL7209286 | 0.76 | KDM4E (0.55) | TDP1L3MBTL1ESR1LMNAMAPT | |
| SCHEMBL8611247 | 0.75 | CYP19A1 (0.51) | ESR1CYP1A2CYP3A4ESR2CYP19A1 | |
| SCHEMBL7032426 | 0.75 | CYP19A1 (0.51) | ESR1CYP1A2CYP3A4ESR2CYP19A1 | |
| SCHEMBL4620169 | 0.75 | GAA (0.51) | ESR1MAPTCYP3A4CYP2D6ESR2 | |
| SCHEMBL10893461 | 0.74 | ALDH1A1 (0.41) | ESR1LMNAMAPTCYP3A4ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019377-B1 | 1-HYDROCARBYLOXYPHENYL-1,2-DIPHENYLALKENE DERIVATIVES, THEIR MANUFACTURE AND A PHARMACEUTICAL COMPOSITION CONTAINING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-08-04 | — | — | EP | disclosed |