Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CCR1 | P32246 | 2/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | CCR8 | P51685 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27992832 | 0.79 | ALDH1A1 (0.43) | ALDH1A1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL28460906 | 0.79 | ALDH1A1 (0.43) | ALDH1A1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL6900112 | 0.78 | ALDH1A1 (0.42) | ALDH1A1NPC1MAPTRAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL6895486 | 0.78 | ALDH1A1 (0.42) | ALDH1A1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL7733562 | 0.76 | ALDH1A1 (0.40) | ALDH1A1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL29213168 | 0.72 | LMNA (0.34) | ALDH1A1MAPTKMT2AHSD17B10LMNA | |
| SCHEMBL483646 | 0.70 | ALDH1A1 (0.62) | ALDH1A1NPC1MAPTRAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL11680674 | 0.68 | ALDH1A1 (0.60) | ALDH1A1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL7824502 | 0.68 | KDM1A (0.32) | — | |
| SCHEMBL6897793 | 0.67 | KDM4E (0.45) | ALDH1A1NPC1MAPTRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033371-B1 | Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2004-01-28 | — | — | EP | disclosed |
| US-6458982-B1 | CATALYST SYSTEM COMPRISING AT LEAST ONE METALLOCENE AND AT LEAST ONE COCATALYST. ON SUPPORT. | TARGOR GMBH (DE) | 2002-10-01 | — | — | US | disclosed |
| EP-1033371-A1 | Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins | TARGOR GmbH (DE) | 2000-09-06 | — | — | EP | disclosed |