SCHEMBL6904748

SCHEMBL6904748

O=C1c2ccc(O)c(O)c2C(=O)c2c1ccc(O)c2O

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.83
MAOA P21397 5/20 0.83
MEN1 O00255 5/20 0.83
KMT2A Q03164 5/20 0.83
ALDH1A1 P00352 4/20 0.83
MAPK1 P28482 4/20 0.83
HPGD P15428 3/20 0.83
ALOX15 P16050 3/20 0.83
HSD17B10 Q99714 3/20 0.83
TDP1 Q9NUW8 3/20 0.83
KDM4E B2RXH2 2/20 0.83
CYP3A4 P08684 2/20 0.83
APEX1 P27695 2/20 0.83
RECQL P46063 2/20 0.83
THRB P10828 2/20 0.83
CSNK2A2 P19784 2/20 0.83
CSNK2B P67870 2/20 0.83
CSNK2A1 P68400 2/20 0.83
CSNK2A3 Q8NEV1 2/20 0.83
USP2 O75604 1/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2772226 0.92 MAPT (0.86) MAPTMAOAMEN1KMT2AALDH1A1
Quinalizarin SCHEMBL20608650 0.91 MAOA (1.00) MAPTMAOAMEN1KMT2AALDH1A1
Quinalizarin SCHEMBL29437816 0.91 MAOA (1.00) MAPTMAOAMEN1KMT2AALDH1A1
Quinalizarin SCHEMBL29516323 0.91 MAOA (1.00) MAPTMAOAMEN1KMT2AALDH1A1
Quinalizarin SCHEMBL138122 0.91 MAOA (1.00) MAPTMAOAMEN1KMT2AALDH1A1
SCHEMBL11055115 0.89 MAPT (0.80) MAPTMAOAMEN1KMT2AALDH1A1
SCHEMBL29929513 0.88 MAOA (0.77) MAPTMAOAMEN1KMT2AALDH1A1
SCHEMBL6901176 0.88 MAOA (0.77) MAPTMAOAMEN1KMT2AALDH1A1
Athraquinones A SCHEMBL18614 0.87 MAPT (1.00) MAPTMAOAMEN1KMT2AALDH1A1
Athraquinones A SCHEMBL4972786 0.87 MAPT (1.00) MAPTMAOAMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6815481-B2 FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-09 US disclosed
US-20020032256-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-14 US disclosed
EP-0320227-B1 Method of preventing polymer-scale formation SHINETSU CHEMICAL CO (JP) 1994-09-07 EP disclosed
US-4933399-A COATING INSIDE OF VESSEL WITH A CATIONIC DYE, DRYING, COATING WITH AN ANIONIC OR AMPHOTERIC POLYMER OR A HYDROXYL-CONTAINING COMPOUND IN A SOLVENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 1990-06-12 US disclosed