Quinalizarin

Quinalizarin

SCHEMBL138122

O=C1c2ccc(O)c(O)c2C(=O)c2c(O)ccc(O)c21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 1.00
MAPT P10636 6/20 1.00
MEN1 O00255 6/20 1.00
KMT2A Q03164 6/20 1.00
HPGD P15428 6/20 1.00
ALDH1A1 P00352 5/20 1.00
MAPK1 P28482 5/20 1.00
TDP1 Q9NUW8 5/20 1.00
ALOX15 P16050 4/20 1.00
HSD17B10 Q99714 4/20 1.00
CYP3A4 P08684 4/20 1.00
KDM4E B2RXH2 3/20 1.00
RECQL P46063 3/20 1.00
CSNK2A2 P19784 3/20 1.00
CSNK2B P67870 3/20 1.00
CSNK2A1 P68400 3/20 1.00
CSNK2A3 Q8NEV1 3/20 1.00
APEX1 P27695 2/20 1.00
BRCA1 P38398 2/20 1.00
THRB P10828 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinalizarin SCHEMBL29516323 1.00 MAOA (1.00) MAOAMAPTMEN1KMT2AHPGD
Quinalizarin SCHEMBL20608650 1.00 MAOA (1.00) MAOAMAPTMEN1KMT2AHPGD
Quinalizarin SCHEMBL29437816 1.00 MAOA (1.00) MAOAMAPTMEN1KMT2AHPGD
SCHEMBL2772226 0.93 MAPT (0.86) MAOAMAPTMEN1KMT2AHPGD
SCHEMBL6904748 0.91 MAPT (0.83) MAOAMAPTMEN1KMT2AHPGD
SCHEMBL11055115 0.89 MAPT (0.80) MAOAMAPTMEN1KMT2AHPGD
SCHEMBL17689250 0.89 MEN1 (0.79) MAOAMAPTMEN1KMT2AHPGD
Quinalizarin SCHEMBL7869031 0.87 MAPT (0.76) MAOAMAPTMEN1KMT2AHPGD
SCHEMBL20457598 0.86 MAOA (0.73) MAOAMAPTMEN1KMT2AHPGD
Quinalizarin SCHEMBL9308575 0.86 MAOA (0.80) MAOAMAPTMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1708 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
US-20240293789-A1 Encapsulation of Functional Additives in Partially-Open Microcapsules SAS Nanotechnologies Inc. 2024-09-05 US claimed
US-11859047-B2 Polycarbonate resin composition and article including the same LG CHEM, LTD. (KR) 2024-01-02 US claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 US claimed
US-20230057309-A1 Inhibitors of DREAM Complex Assembly and/or Function For Use In Repairing DNA Damage H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. 2023-02-23 US claimed
US-11577212-B2 Stimuli-responsive micro-reservoirs for release of encapsulants SAS Nanotechnologies Inc. (US) 2023-02-14 US claimed
EP-4091611-A1 INHIBITORS OF DREAM COMPLEX ASSEMBLY AND/OR FUNCTION FOR USE IN REPAIRING DNA DAMAGE Schumacher, Björn (DE) 2022-11-23 EP claimed
EP-4091610-A1 INHIBITORS OF DREAM COMPLEX ASSEMBLY AND/OR FUNCTION FOR USE IN REPAIRING DNA DAMAGE Schumacher, Björn (DE) 2022-11-23 EP claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
US-5032526-A Method for the colorimetric determination of sulfonates in aqueous systems CALGON CORPORATION (US) 1991-07-16 US claimed
US-4894346-A Method for the colorimetric determination of polycarboxylates in aqueous systems CALGON CORPORATION (US) 1990-01-16 US claimed
EP-0348509-A1 ANTI-RETROVIRAL DRUG TSUMURA & CO. (JP) 1990-01-03 EP claimed
EP-0144130-B1 METHOD FOR THE COLORIMETRIC DETERMINATION OF POLYGARBOXYLATES AND SULPHONATES INAQUEOUS SYSTEMS CALGON CORPORATION (US) 1989-03-01 EP claimed
US-4769228-A Method of reducing sulfur deposition in hydrogen sulfide equipment CHEVRON RESEARCH COMPANY (US) 1988-09-06 US claimed
US-4602913-A Use of hydroxyanthraquinones for the coloration of human keratin fibres L'OREAL (FR) 1986-07-29 US claimed
US-H72-H Organic substitutes for charcoal in black powder THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1986-06-03 US claimed
US-4529707-A Detection of boron impurities in chlorosilanes GENERAL ELECTRIC COMPANY (US) 1985-07-16 US claimed
EP-0144130-A1 Method for the colorimetric determination of polygarboxylates and sulphonates inaqueous systems CALGON CORPORATION (US) 1985-06-12 EP claimed
US-3992311-A Reactive developer for electrophotography METCALFE KENNETH A 1976-11-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB MAOA 3718/4885MAPT 3926/4885MEN1 1711/4885
US-11577212-B2 Stimuli-responsive micro-reservoirs for release of encapsulants ORAI1, CD44, VAPA MAOA 147/4885MAPT 3648/4885MEN1 1542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.