SCHEMBL6904779

SCHEMBL6904779

Cc1cc(O)c2c(=O)c3c(O)cc(O)cc3oc2c1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 7/20 0.79
GAA P10253 5/20 0.79
SI P14410 3/20 0.79
MGAM2 Q2M2H8 3/20 0.79
PIM1 P11309 3/20 0.75
PLK1 P53350 3/20 0.75
NUAK1 O60285 2/20 0.75
IGF1R P08069 2/20 0.75
SRC P12931 2/20 0.75
KDR P35968 2/20 0.75
PKN1 Q16512 2/20 0.75
AURKB Q96GD4 2/20 0.75
ALK Q9UM73 2/20 0.75
MET P08581 1/20 0.69
AXL P30530 1/20 0.69
NEK2 P51955 1/20 0.69
PTK2 Q05397 1/20 0.69
NEK6 Q9HC98 1/20 0.69
MAOA P21397 5/20 0.63
FASN P49327 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30542658 0.89 MGAM (1.00) MGAMGAASIMGAM2PIM1
SCHEMBL9838561 0.89 MGAM (1.00) MGAMGAASIMGAM2PIM1
Norlichexanthone SCHEMBL31619305 0.86 PIM1 (1.00) MGAMGAASIMGAM2PIM1
Norlichexanthone SCHEMBL31619312 0.86 PIM1 (1.00) MGAMGAASIMGAM2PIM1
SCHEMBL28336570 0.82 MGAM (0.66) MGAMGAASIMGAM2PIM1
SCHEMBL29800692 0.81 PIM1 (0.73) MGAMGAASIMGAM2PIM1
Anomalin A SCHEMBL29780138 0.81 PIM1 (1.00) MGAMGAASIMGAM2PIM1
SCHEMBL9838552 0.79 MGAM (0.79) MGAMGAASIMGAM2PIM1
SCHEMBL1858144 0.79 MGAM (0.67) MGAMGAASIMGAM2PIM1
Lachnone A SCHEMBL30163008 0.79 ALDH1A1 (0.53) MGAMGAASIMGAM2PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6815481-B2 FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-09 US disclosed
US-20020032256-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-14 US disclosed