Lachnone A

Lachnone A

SCHEMBL30163008

Cc1cc(O)c2c(=O)c(O)c(C)oc2c1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.53
GAA P10253 5/20 0.53
HPGD P15428 4/20 0.53
HTT P42858 3/20 0.53
PPARG P37231 3/20 0.53
MAPK1 P28482 2/20 0.53
RXFP1 Q9HBX9 2/20 0.53
MAPK10 P53779 1/20 0.53
NCOA2 Q15596 1/20 0.53
ALOX15 P16050 4/20 0.48
TSHR P16473 1/20 0.48
KDM4C Q9H3R0 1/20 0.48
PIM1 P11309 3/20 0.47
PLK1 P53350 3/20 0.47
NUAK1 O60285 2/20 0.47
IGF1R P08069 2/20 0.47
SRC P12931 2/20 0.47
KDR P35968 2/20 0.47
PKN1 Q16512 2/20 0.47
AURKB Q96GD4 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1858144 0.86 MGAM (0.67) ALDH1A1GAAHPGDPPARGMAPK1
SCHEMBL12305080 0.79 MEN1 (0.73) ALDH1A1GAAHPGDPPARGMAPK1
SCHEMBL6904779 0.79 MGAM (0.79) ALDH1A1GAAHPGDHTTPPARG
SCHEMBL23919099 0.78 MEN1 (0.65) ALDH1A1GAAHPGDHTTPPARG
SCHEMBL14769773 0.77 MEN1 (0.76) ALDH1A1GAAHPGDPPARGMAPK1
SCHEMBL796920 0.76 MAPT (0.58) ALDH1A1HPGDMAPK1ALOX15MAPT
SCHEMBL9909444 0.76 MEN1 (0.75) ALDH1A1GAAHPGDHTTPPARG
SCHEMBL14254533 0.75 MEN1 (0.58) ALDH1A1GAAHPGDPPARGMAPK1
SCHEMBL12457526 0.73 ALDH1A1 (0.74) ALDH1A1GAAHPGDHTTPPARG
SCHEMBL12455834 0.73 CYP1A1 (0.79) ALDH1A1HPGDPPARGALOX15MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111108106-B Heterocyclic derivatives as pest control agents 拜耳公司 2023-02-03 CN disclosed