Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SELL | P14151 | 1/20 | 0.44 |
| ▸ | SELP | P16109 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | IAPP | P10997 | 1/20 | 0.43 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8607932 | 0.86 | HMGB1 (0.60) | HMGB1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL19900571 | 0.85 | HMGB1 (0.68) | HMGB1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL29619558 | 0.82 | FOLH1 (0.55) | HMGB1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL2559743 | 0.82 | FOLH1 (0.55) | HMGB1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL39623 | 0.82 | HMGB1 (0.65) | HMGB1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL29695710 | 0.82 | HMGB1 (0.65) | HMGB1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28853970 | 0.81 | FOLH1 (0.49) | HMGB1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL27360496 | 0.81 | HMGB1 (0.62) | HMGB1ALDH1A1KDM4EHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL11527302 | 0.81 | HMGB1 (0.62) | HMGB1ALDH1A1KDM4EHPGDHSD17B10 | |
| Bicarbonate SCHEMBL237485 | 0.81 | HMGB1 (0.62) | HMGB1ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58172348-A | — | — | None | — | — | JP | disclosed |
| US-6777508-B1 | HIGHLY ACTIVE AND HIGHLY STEREOSPECIFIC CATALYSTS FOR THE POLYMERIZATION OF PROPYLENE AND HIGHER OLEFINS | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2004-08-17 | — | — | US | disclosed |
| US-6194342-B1 | COMPRISING REACTION PRODUCT OF ALUMINUM ALKYL COMPOUND, A SILICON COMPOUND CONTAINING ONE SI--OR OR SI--OCOR OR SI--NR2 BOND, R BEING HYDROCARBYL RADICAL, A SOLID COMPRISING AS SUPPORT A MAGNESIUM DIHALIDE AND A TITANIUM HALIDE | MONTELL TECHNOLOGY COMPANY BV (NL) | 2001-02-27 | — | — | US | disclosed |
| EP-0045977-B2 | Components and catalysts for the polymerization of olefins | MONTEDISON SPA (IT) | 1995-03-15 | — | — | EP | disclosed |
| US-5151415-A | Method of treating a papova-type viral infection | SIRANY DALLAS (US) | 1992-09-29 | — | — | US | disclosed |
| US-4987127-A | Method of treating a virus outbreak | SIRANY DAL (US) | 1991-01-22 | — | — | US | disclosed |
| EP-0045977-B1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | Montedison S.p.A. (IT) | 1987-01-07 | — | — | EP | disclosed |
| JP-S58172348-A | PREPARATION OF 3-PROPIONYLSALICYLIC ACID DERIVATIVE | MITSUI PETROCHEM IND LTD | 1983-10-11 | — | — | JP | disclosed |
| EP-0045977-A2 | Components and catalysts for the polymerization of olefins | Montedison S.p.A. (IT) | 1982-02-17 | — | — | EP | disclosed |