Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.59 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | GGT1 | P19440 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29158556 | 0.86 | KDM4E (0.61) | KDM4EHTTALDH1A1KMT2APTK2B | |
| SCHEMBL3316012 | 0.86 | KDM4E (0.65) | KDM4EHTTALDH1A1KMT2APTK2B | |
| SCHEMBL16966571 | 0.86 | KDM4E (0.65) | KDM4EHTTALDH1A1KMT2APTK2B | |
| SCHEMBL29502958 | 0.85 | KDM4E (0.73) | KDM4EHTTALDH1A1KMT2APTK2B | |
| SCHEMBL341639 | 0.85 | KDM4E (0.73) | KDM4EHTTALDH1A1KMT2APTK2B | |
| SCHEMBL3314748 | 0.84 | KDM4E (0.63) | KDM4EHTTALDH1A1KMT2APTK2B | |
| SCHEMBL2955119 | 0.84 | KMT2A (0.62) | KDM4EHTTALDH1A1KMT2AHSD17B10 | |
| SCHEMBL7718767 | 0.84 | MAPT (0.59) | KDM4EHTTALDH1A1KMT2ALMNA | |
| SCHEMBL10335500 | 0.83 | KDM4E (0.61) | KDM4EHTTALDH1A1KMT2APTK2B | |
| SCHEMBL4237868 | 0.82 | KDM4E (0.65) | KDM4EHTTALDH1A1KMT2APTK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117180-A1 | AZAHETEROCYCLES, COMBINATORY LIBRARY, FOCUSED LIBRARY, PHARMACEUTICAL COMPOSITION AND METHODS FOR THE PRODUCTION THEREOF | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE' LTD. (RU) | 2007-10-18 | — | — | WO | disclosed |
| US-6777508-B1 | HIGHLY ACTIVE AND HIGHLY STEREOSPECIFIC CATALYSTS FOR THE POLYMERIZATION OF PROPYLENE AND HIGHER OLEFINS | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2004-08-17 | — | — | US | disclosed |
| US-6194342-B1 | COMPRISING REACTION PRODUCT OF ALUMINUM ALKYL COMPOUND, A SILICON COMPOUND CONTAINING ONE SI--OR OR SI--OCOR OR SI--NR2 BOND, R BEING HYDROCARBYL RADICAL, A SOLID COMPRISING AS SUPPORT A MAGNESIUM DIHALIDE AND A TITANIUM HALIDE | MONTELL TECHNOLOGY COMPANY BV (NL) | 2001-02-27 | — | — | US | disclosed |
| EP-0045977-B2 | Components and catalysts for the polymerization of olefins | MONTEDISON SPA (IT) | 1995-03-15 | — | — | EP | disclosed |
| US-5151415-A | Method of treating a papova-type viral infection | SIRANY DALLAS (US) | 1992-09-29 | — | — | US | disclosed |
| US-4987127-A | Method of treating a virus outbreak | SIRANY DAL (US) | 1991-01-22 | — | — | US | disclosed |
| EP-0045977-B1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | Montedison S.p.A. (IT) | 1987-01-07 | — | — | EP | disclosed |
| EP-0045977-A2 | Components and catalysts for the polymerization of olefins | Montedison S.p.A. (IT) | 1982-02-17 | — | — | EP | disclosed |