SCHEMBL3316012

SCHEMBL3316012

C=C(C)COc1ccccc1C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.65
HTT P42858 2/20 0.65
ALDH1A1 P00352 7/20 0.57
KMT2A Q03164 2/20 0.57
PTK2B Q14289 1/20 0.57
HSD17B10 Q99714 6/20 0.56
HPGD P15428 4/20 0.56
ESR1 P03372 1/20 0.56
ITGB3 P05106 1/20 0.56
ITGA2B P08514 1/20 0.56
HMGB1 P09429 1/20 0.56
TSHR P16473 1/20 0.56
GGT1 P19440 1/20 0.56
PTGS1 P23219 1/20 0.56
PTGS2 P35354 1/20 0.56
BLM P54132 1/20 0.56
NAPRT Q6XQN6 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
LMNA P02545 2/20 0.50
CYP1A2 P05177 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16966571 1.00 KDM4E (0.65) KDM4EHTTALDH1A1KMT2APTK2B
SCHEMBL3314748 0.98 KDM4E (0.63) KDM4EHTTALDH1A1KMT2APTK2B
SCHEMBL6904968 0.86 KDM4E (0.69) KDM4EHTTALDH1A1KMT2APTK2B
SCHEMBL14092915 0.86 KDM4E (0.46) KDM4EHTTALDH1A1KMT2APTK2B
SCHEMBL538221 0.85 ELANE (0.51) KDM4EHTTKMT2AGPR174MEN1
SCHEMBL5382362 0.85 MAPT (0.56) KDM4EHTTALDH1A1KMT2ALMNA
SCHEMBL8379922 0.83 ALDH1A1 (0.56) KDM4EHTTALDH1A1KMT2AHPGD
SCHEMBL3314743 0.83 KDM4E (0.45) KDM4EHTTALDH1A1KMT2AHPGD
SCHEMBL21545998 0.83 MAPT (0.50) KDM4EHTTALDH1A1KMT2AHSD17B10
SCHEMBL9645622 0.83 KDM4E (0.65) KDM4EHTTALDH1A1KMT2APTK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115872661-B Viscosity-reducing polycarboxylate superplasticizer and preparation method thereof 科之杰新材料集团有限公司 2024-02-20 CN claimed
CN-115872661-A Viscosity-reducing polycarboxylate superplasticizer and preparation method thereof 科之杰新材料集团有限公司 2023-03-31 CN claimed
EP-0334778-B1 AROMATIC POLYAMIDE-IMIDES FUNCTIONALISED WITH ALKENYLOXY GROUPS, A METHOD FOR THEIR PREPARATION AND THEIR USE TO PREPARE CROSSLINKED POLYMERS CIBA-GEIGY AG (CH) 1992-04-15 EP claimed
US-4927899-A Alkenyloxylated aromatic polyamidoimides RHONE-POULENC CHIMIE (FR) 1990-05-22 US claimed
EP-0296220-A4 WETTABLE, HYDROPHILIC, SOFT AND OXYGEN PERMEABLE COPOLYMER COMPOSITIONS. CHANG SING-HSIUNG (US) 1989-05-11 EP claimed
EP-0296220-A1 WETTABLE, HYDROPHILIC, SOFT AND OXYGEN PERMEABLE COPOLYMER COMPOSITIONS CHANG, Sing-Hsiung (US) 1988-12-28 EP claimed
WO-1988005060-A1 WETTABLE, HYDROPHILIC, SOFT AND OXYGEN PERMEABLE COPOLYMER COMPOSITIONS CHANG SING HSIUNG (US) 1988-07-14 WO claimed
CN-115872661-B Viscosity-reducing polycarboxylate superplasticizer and preparation method thereof 科之杰新材料集团有限公司 2024-02-20 CN disclosed
CN-115872661-A Viscosity-reducing polycarboxylate superplasticizer and preparation method thereof 科之杰新材料集团有限公司 2023-03-31 CN disclosed
CN-107266318-B Polysiloxane compound, method for preparing the same, and copolycarbonate resin comprising the same LG化学株式会社 2020-07-03 CN disclosed
EP-2520579-B1 A silicone compound, photocurable liquid ink using the silicone compound, and method of manufacturing the ink RICOH CO LTD (JP) 2015-08-05 EP disclosed
US-8871861-B2 Silicone compound, photocurable liquid ink using the silicone compound, and method of manufacturing the ink RICOH COMPANY, LTD. (JP) 2014-10-28 US disclosed
US-8466199-B2 Allyloxy and alkyloxy benzoic acid delivery agents EMISPHERE TECHNOLOGIES, INC. (US) 2013-06-18 US disclosed
US-4927899-A Alkenyloxylated aromatic polyamidoimides RHONE-POULENC CHIMIE (FR) 1990-05-22 US disclosed
US-4921982-A 5-halo-2,3-dihydro-2,2-dimethylbenzofuran-7-carboxylic acids useful as intermediates for 5-HT3 antagonists ELI LILLY AND COMPANY (US) 1990-05-01 US disclosed
EP-0296220-A4 WETTABLE, HYDROPHILIC, SOFT AND OXYGEN PERMEABLE COPOLYMER COMPOSITIONS. CHANG SING-HSIUNG (US) 1989-05-11 EP disclosed
EP-0307172-A2 Improvements in or relating to specific 5-HT3 antagonists ELI LILLY AND COMPANY (US) 1989-03-15 EP disclosed
EP-0296220-A1 WETTABLE, HYDROPHILIC, SOFT AND OXYGEN PERMEABLE COPOLYMER COMPOSITIONS CHANG, Sing-Hsiung (US) 1988-12-28 EP disclosed
WO-1988005060-A1 WETTABLE, HYDROPHILIC, SOFT AND OXYGEN PERMEABLE COPOLYMER COMPOSITIONS CHANG SING HSIUNG (US) 1988-07-14 WO disclosed
EP-0252603-A2 Adhesives for ceramics and processes for the bonding of ceramics using same MITSUI SEKIYU KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-01-13 EP disclosed