Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | GGT1 | P19440 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3316012 | 0.98 | KDM4E (0.65) | KDM4EHTTALDH1A1KMT2APTK2B | |
| SCHEMBL16966571 | 0.98 | KDM4E (0.65) | KDM4EHTTALDH1A1KMT2APTK2B | |
| SCHEMBL6904968 | 0.84 | KDM4E (0.69) | KDM4EHTTALDH1A1KMT2APTK2B | |
| SCHEMBL14092915 | 0.84 | KDM4E (0.46) | KDM4EHTTALDH1A1KMT2APTK2B | |
| SCHEMBL538221 | 0.84 | ELANE (0.51) | KDM4EHTTKMT2AGPR174MEN1 | |
| SCHEMBL5382362 | 0.83 | MAPT (0.56) | KDM4EHTTALDH1A1KMT2ALMNA | |
| SCHEMBL3314743 | 0.82 | KDM4E (0.45) | KDM4EHTTALDH1A1KMT2AHPGD | |
| SCHEMBL8379922 | 0.82 | ALDH1A1 (0.56) | KDM4EHTTALDH1A1KMT2AHPGD | |
| SCHEMBL21545998 | 0.81 | MAPT (0.50) | KDM4EHTTALDH1A1KMT2AHSD17B10 | |
| SCHEMBL9645622 | 0.81 | KDM4E (0.65) | KDM4EHTTALDH1A1KMT2APTK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466199-B2 | Allyloxy and alkyloxy benzoic acid delivery agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2013-06-18 | — | — | US | disclosed |
| US-20100105604-A1 | ALLYLOXY AND ALKYLOXY BENZOIC ACID DELIVERY AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2010-04-29 | — | — | US | disclosed |
| EP-2136624-A1 | ALLYLQXY AND ALKYLOXY BENZOIC ACID DELIVERY AGENTS | Emisphere Technologies, Inc. (US) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008116141-A1 | ALLYLQXY AND ALKYLOXY BENZOIC ACID DELIVERY AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2008-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105604-A1 | ALLYLOXY AND ALKYLOXY BENZOIC ACID DELIVERY AGENTS | ABCB11, TSPO, AADAC | KDM4E 2914/4885HTT 749/4885ALDH1A1 196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.