SCHEMBL6905016

SCHEMBL6905016

CCC12CC3CC(C)(CC(O)(C3)C1)C2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
GRIN1 Q05586 9/20 0.46
GRIN2A Q12879 9/20 0.46
GRIN2D O15399 8/20 0.46
GRIN3B O60391 8/20 0.46
GRIN2B Q13224 8/20 0.46
GRIN2C Q14957 8/20 0.46
GRIN3A Q8TCU5 8/20 0.46
HTT P42858 2/20 0.38
LMNA P02545 2/20 0.35
SLC22A1 O15245 1/20 0.35
ESR1 P03372 1/20 0.35
ADRB3 P13945 1/20 0.35
ACHE P22303 1/20 0.35
OPRK1 P41145 1/20 0.35
MTOR P42345 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14837319 0.86 GRIN2D (0.57) MEN1KMT2AGRIN1GRIN2AGRIN2D
SCHEMBL2571225 0.86 GRIN2D (0.52) MEN1KMT2AGRIN1GRIN2AGRIN2D
SCHEMBL4034262 0.85 MEN1 (0.47) MEN1KMT2AGRIN1GRIN2AGRIN2D
SCHEMBL1940153 0.84 MEN1 (0.63) MEN1KMT2AGRIN1GRIN2AGRIN2D
SCHEMBL25472233 0.80 GRIN1 (0.52) MEN1KMT2AGRIN1GRIN2AGRIN2D
SCHEMBL986905 0.80 GRIN1 (0.46) MEN1KMT2AGRIN1GRIN2AGRIN2D
SCHEMBL733948 0.80 GRIN1 (0.52) MEN1KMT2AGRIN1GRIN2AGRIN2D
SCHEMBL11701304 0.79 GRIN1 (0.60) MEN1KMT2AGRIN1GRIN2AGRIN2D
SCHEMBL11657544 0.74 MEN1 (0.47) MEN1KMT2AGRIN1GRIN2AGRIN2D
SCHEMBL657398 0.74 GRIN1 (0.75) MEN1KMT2AGRIN1GRIN2AGRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481016-B2 Method for inhibition of potential-dependent cation channel KAO CORPORATION (JP) 2013-07-09 US disclosed
US-20130045177-A1 Method for Inhibition of Potential-Dependent Cation Channel KAO CORPORATION (JP) 2013-02-21 US disclosed
EP-1258292-B1 Oxidation catalytic system and oxidation process using same DAICEL CHEM (JP) 2004-05-19 EP disclosed
EP-0824962-B1 USE OF AN OXIDATION CATALYST SYSTEM AND PROCESS FOR OXIDATION WITH THE SAME DAICEL CHEM (JP) 2003-05-07 EP disclosed
EP-0858835-B1 Oxidation catalytic system and oxidation process DAICEL CHEM (JP) 2003-05-07 EP disclosed
CN-1098124-C Oxidation catalyst system and process for oxidation with the same DAICEL CHEM (JP) 2003-01-08 CN disclosed
EP-1258292-A1 Oxidation catalytic system and oxidation process using same DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-11-20 EP disclosed
US-5981420-A OXIDATION CATALYSTS SYSTEM CONSISTS OF AN N-HYDROXY OR N-OXY IMIDE COMPOUND AND A TRANSITION METAL COMPOUND EXCLUDING A POLYACID AS COCATALYST DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1999-11-09 US disclosed
US-5958821-A EPOXIDATION OF AN ALKENE USING A CYCLIC N-HYDROXYIMIDE AND A COCATALYST OF A COMPOUND OF A GROUP 2A OR TRANSITION METAL USING OXYGEN; CATALYST SELECTIVITY; FREE OF PHOSPHO-VANADOMOLYBDIC ACID OR TETRAPHENYLPORPHYRINTOATO MANGANESE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1999-09-28 US disclosed
EP-0858835-A1 Oxidation catalytic system and oxidation process Daicel Chemical Industries, Ltd. (JP) 1998-08-19 EP disclosed
EP-0144712-B1 OPTICAL FIBER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-03-30 EP disclosed
US-4717756-A HYDROPEROXIDE INITIATOR, SULFUR REDUCTANT, HYDROGEN HALOGENIDE SALT, COPPER COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-01-05 US disclosed
EP-0231395-A1 PROCESS FOR PRODUCING METHACRYLATE POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-08-12 EP disclosed
EP-0217545-A1 Method for the production of polymethacrylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-04-08 EP disclosed
EP-0190656-A2 Method for producing plastic optical fiber with heat resistance SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-08-13 EP disclosed
US-4576438-A Heat-resisting optical fiber SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-03-18 US disclosed
EP-0162472-A2 Plastic optical fiber SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-11-27 EP disclosed
EP-0154339-A2 Optical fiber SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-09-11 EP disclosed
EP-0144712-A2 Optical fiber SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-06-19 EP disclosed
EP-0097325-A2 Optical fiber SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-01-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130045177-A1 Method for Inhibition of Potential-Dependent Cation Channel TRPM7, TRPM8, OR10J3 MEN1 2194/4885KMT2A 3964/4885GRIN1 215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.