SCHEMBL6905352

SCHEMBL6905352

CC(C)C1c2cc(O)ccc2Oc2ccc(O)cc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPKAPK2 P49137 2/20 0.44
ALDH1A1 P00352 7/20 0.41
HPGD P15428 6/20 0.41
GLA P06280 1/20 0.41
MAPT P10636 4/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
HSD17B10 Q99714 2/20 0.40
GAA P10253 1/20 0.40
DYRK1A Q13627 1/20 0.36
CYP3A4 P08684 2/20 0.35
CYP2C9 P11712 1/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
CASP1 P29466 1/20 0.35
BRCA1 P38398 1/20 0.35
STAT6 P42226 1/20 0.35
CASP7 P55210 1/20 0.35
HBB P68871 1/20 0.35
HIF1A Q16665 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16755711 0.85 MAPKAPK2 (0.44) MAPKAPK2ALDH1A1HPGDMAPTMEN1
SCHEMBL14301526 0.81 MEN1 (0.45) MAPKAPK2ALDH1A1HPGDMAPTMEN1
SCHEMBL6906648 0.78 ALDH1A1 (0.44) MAPKAPK2ALDH1A1HPGDGLAMAPT
SCHEMBL20099446 0.74 MAPKAPK2 (0.43) MAPKAPK2ALDH1A1MAPTMEN1KMT2A
SCHEMBL6905793 0.73 ESR1 (0.44) MAPKAPK2ALDH1A1HPGDGLAMAPT
SCHEMBL12205453 0.72 KMT2A (0.49) MAPTKMT2AGAACYP2C9L3MBTL1
SCHEMBL12205456 0.71 MAOA (0.52) MAPTMEN1KMT2ACYP3A4CYP2C9
SCHEMBL17797155 0.68 ALDH1A1 (0.47) ALDH1A1HPGDGLAMAPTMEN1
SCHEMBL5030661 0.68 ALDH1A1 (0.56) ALDH1A1HPGDGLAMAPTMEN1
SCHEMBL27495377 0.67 KMT2A (0.45) MAPKAPK2ALDH1A1HPGDGLAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6815481-B2 FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-09 US disclosed
US-20020032256-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-14 US disclosed