Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 6/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.52 |
| ▸ | ACLY | P53396 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27865564 | 0.80 | ACLY (0.70) | ACLYMAOAMEN1MAPTKMT2A | |
| SCHEMBL31017308 | 0.78 | BCL2 (0.76) | BCL2MCL1ACLYMAOAMEN1 | |
| SCHEMBL29665051 | 0.78 | BCL2 (0.76) | BCL2MCL1ACLYMAOAMEN1 | |
| SCHEMBL1230309 | 0.78 | BCL2 (0.76) | BCL2MCL1ACLYMAOAMEN1 | |
| SCHEMBL11303845 | 0.70 | MCL1 (0.60) | BCL2MCL1MAOAMEN1MAPT | |
| SCHEMBL11303850 | 0.70 | MCL1 (0.57) | BCL2MCL1MAOAMEN1MAPT | |
| SCHEMBL28919903 | 0.68 | ALOX15 (0.50) | ALDH1A1CYP3A4HPGDALOX15MAPK1 | |
| SCHEMBL555230 | 0.68 | BCL2 (1.00) | BCL2MCL1MAOAMEN1MAPT | |
| SCHEMBL17867446 | 0.68 | BCL2 (0.61) | BCL2MCL1ACLYMAOAMEN1 | |
| SCHEMBL6904535 | 0.68 | BCL2 (0.61) | BCL2MCL1MAOAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815481-B2 | FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-09 | — | — | US | disclosed |
| US-20020032256-A1 | Polybutadiene composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-03-14 | — | — | US | disclosed |