Sugi Predict

Sugi Predict / Compounds / SCHEMBL1921628

SCHEMBL1921628

SCHEMBL1921628

Clc1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.59
▸ NPC1 O15118 1/20 0.59
▸ ALDH1A1 P00352 1/20 0.59
▸ LMNA P02545 1/20 0.59
▸ MAPT P10636 1/20 0.59
▸ HPGD P15428 1/20 0.59
▸ RAB9A P51151 1/20 0.59
▸ SMN1; SMN2 Q16637 1/20 0.59
▸ CYP1A2 P05177 3/20 0.56
▸ ITGA1 P56199 1/20 0.54
▸ SRD5A2 P31213 1/20 0.52
▸ HSP90AA1 P07900 1/20 0.51
▸ DRD2 P14416 4/20 0.49
▸ DRD4 P21917 4/20 0.49
▸ CA1 P00915 1/20 0.49
▸ CA2 P00918 1/20 0.49
▸ CA4 P22748 1/20 0.49
▸ CA6 P23280 1/20 0.49
▸ CYP3A4 P08684 1/20 0.49
▸ METAP1 P53582 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3785566 0.91 ITGA1 (0.54) KDM4ENPC1ALDH1A1LMNAMAPT
SCHEMBL1922789 0.89 METAP1 (0.57) CYP1A2SRD5A2HSP90AA1CA1CA2
SCHEMBL29572171 0.89 METAP1 (0.57) CYP1A2SRD5A2HSP90AA1CA1CA2
SCHEMBL10694841 0.88 MAOA (0.67) KDM4ENPC1ALDH1A1LMNAMAPT
SCHEMBL23372333 0.88 MAOA (0.57) KDM4ENPC1ALDH1A1LMNAMAPT
SCHEMBL23372315 0.88 HPGD (0.59) KDM4ENPC1ALDH1A1LMNAMAPT
SCHEMBL23862684 0.84 CNR1 (0.60) KDM4ENPC1ALDH1A1LMNAMAPT
SCHEMBL31196698 0.84 HTR2A (0.45) HPGDCYP1A2ITGA1DRD2DRD4
SCHEMBL31196699 0.84 HTR2A (0.45) HPGDCYP1A2ITGA1DRD2DRD4
SCHEMBL6905658 0.84 HTR2A (0.45) HPGDCYP1A2ITGA1DRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118895515-A Application of platinum carbon catalyst-loaded electrode in aryl compound benzyl carbon-hydrogen bond oxidation reaction 南京航空航天大学 2024-11-05 — — CN claimed
CN-110819295-A Fireproof flame-retardant adhesive 佛山市高建硅胶实业有限公司 2020-02-21 — — CN claimed
CN-108586189-A A kind of recovery and treatment method of 2,7- dichloros fluorenes reaction mother liquor 绍兴文理学院 2018-09-28 — — CN claimed
CN-105884571-B Chloro- 9,9 '-spiral shell, two fluorenes of 2- and its synthetic method 河南省科学院化学研究所有限公司 2018-06-12 — — CN claimed
CN-105884571-A 2-chloro-9,9'-spirobifluorene and synthesis method thereof 河南省科学院化学研究所有限公司 2016-08-24 — — CN claimed
EP-0095880-B1 FLUORENECARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE AS PLANT GROWTH REGULATORS SDS BIOTECH CORPORATION (US) 1986-01-02 — — EP claimed
CN-116375659-B Organic compound, and electronic component and electronic device including the same 陕西莱特光电材料股份有限公司 2025-05-06 — — CN disclosed
CN-116751137-B Method for preparing chloro aromatic compound by photo-induced nitroarene denitration chlorination 华中师范大学 2025-03-07 — — CN disclosed
CN-119306566-A Synthesis method of bromohydrogenation polycyclic aromatic hydrocarbon 浙江巨化技术中心有限公司 2025-01-14 — — CN disclosed
CN-118895515-A Application of platinum carbon catalyst-loaded electrode in aryl compound benzyl carbon-hydrogen bond oxidation reaction 南京航空航天大学 2024-11-05 — — CN disclosed
WO-2024087586-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT COMPRISING SAME, AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2024-05-02 — — WO disclosed
CN-115960001-B Organic compound, and electronic component and electronic device including the same 陕西莱特光电材料股份有限公司 2024-04-19 — — CN disclosed
US-11917908-B2 Organic compound, optical device, light-emitting device, light-emitting apparatus, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-02-27 — — US disclosed
US-5173489-A α,α-disubstituted aromatics and heteroaromatics as cognition enhancers THE DUPONT MERCK PHARMACEUTICAL CO. (US) 1992-12-22 — — US disclosed
US-4968809-A Spirofluoreneisothiazolidinone dioxides as aldose reductase inhibitors NESTLE S.A. A COMPANY OF SWITZERLAND (CH) 1990-11-06 — — US disclosed
EP-0311010-A2 Alpha,Alpha-disubstituted aromatics and heteroaromatics as cognition enhancers THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1989-04-12 — — EP disclosed
EP-0095880-B1 FLUORENECARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE AS PLANT GROWTH REGULATORS SDS BIOTECH CORPORATION (US) 1986-01-02 — — EP disclosed
EP-0011770-B1 FLUORENYL-AZOLYLMETHYL-CARBINOLS, PROCESS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM AND METHOD FOR PREPARING OF THESE MEDICAMENTS BAYER AG (DE) 1981-10-14 — — EP disclosed
US-4239765-A ANTIMYCOTIC AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1980-12-16 — — US disclosed
EP-0011770-A1 Fluorenyl-azolylmethyl-carbinols, process for their preparation, medicaments containing them and method for preparing of these medicaments BAYER AG (DE) 1980-06-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11917908-B2 Organic compound, optical device, light-emitting device, light-emitting apparatus, electronic device, and lighting device NR2E3, AOX1, CYP1A1 KDM4E 4241/4885NPC1 1938/4885ALDH1A1 100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.